[68Ga]Ga-PSMA-11 PET baseline imaging as a prognostic tool for clinical outcomes to [177Lu]Lu-PSMA-617 in patients with mCRPC: A VISION substudy.
…, R Garje, JM Michalski, S Ghebremariam, M Brackman… - 2022 - ascopubs.org
5002 Background: In the phase 3 VISION study, gallium ( 68 Ga) gozetotide ( 68 Ga-PSMA-11)
PET/CT imaging was used to determine eligibility for lutetium ( 177 Lu) vipivotide …
PET/CT imaging was used to determine eligibility for lutetium ( 177 Lu) vipivotide …
[177Lu]Lu-PSMA-617 in PSMA-positive metastatic castration-resistant prostate cancer: Prior and concomitant treatment subgroup analyses of the VISION trial.
…, J Nagarajah, TM Beer, G El-Haddad, M Brackman… - 2022 - ascopubs.org
[177Lu]Lu-PSMA-617 in PSMA-positive metastatic castration-resistant prostate cancer: Prior
and concomitant treatment subgroup analyses of the VISION trial. | Journal of Clinical …
and concomitant treatment subgroup analyses of the VISION trial. | Journal of Clinical …
A VISION substudy of reader agreement on 68Ga-PSMA-11 PET/CT scan interpretation to determine patient eligibility for 177Lu-PSMA-617 radioligand therapy
…, MS Hofman, BJ Krause, M Brackman… - Journal of Nuclear …, 2023 - Soc Nuclear Med
[ 68 Ga]Ga-PSMA-11 ( 68 Ga-PSMA-11) is used to identify prostate-specific membrane antigen
(PSMA)–positive tumors on PET scans. In the VISION study, 68 Ga-PSMA-11 was used …
(PSMA)–positive tumors on PET scans. In the VISION study, 68 Ga-PSMA-11 was used …
Pharmacokinetics and bioavailability of a new formulation of teicoplanin following intravenous and intramuscular administration to humans
…, MT Kenny, JK Dulworth, MB Brackman… - Journal of …, 1991 - Elsevier
Pharmacokinetics, bioavailability, and local tolerance (at the site of intramuscular administration)
of a new formulation of teicoplanin (400 mg/3 mL) were investigated in 24 normal, …
of a new formulation of teicoplanin (400 mg/3 mL) were investigated in 24 normal, …
PCR-Based Ordered Genomic Libraries: a New Approach to Drug Target Identification for Streptococcus pneumoniae
AE Belanger, A Lai, MA Brackman… - Antimicrobial agents …, 2002 - Am Soc Microbiol
Described here are the development and validation of a novel approach to identify genes
encoding drug targets in Streptococcus pneumoniae. The method relies on the use of an …
encoding drug targets in Streptococcus pneumoniae. The method relies on the use of an …
In vitro activity of the semisynthetic glycopeptide amide MDL 63,246
MT Kenny, MA Brackman… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The in vitro activity of the semisynthetic glycopeptide amide MDL 63,246 against 293 US
clinical isolates of gram-positive cocci was determined by the broth microdilution method. When …
clinical isolates of gram-positive cocci was determined by the broth microdilution method. When …
Operational challenges and solutions with implementation of an adaptive seamless phase 2/3 study
K Spencer, K Colvin, B Braunecker, M Brackman… - 2012 - journals.sagepub.com
A wide variety of operational issues were encountered with the planning and implementation
of an adaptive, dose-finding, seamless phase 2/3 trial for a diabetes therapeutic. …
of an adaptive, dose-finding, seamless phase 2/3 trial for a diabetes therapeutic. …
Comparison of agar dilution, tube dilution, and broth microdilution susceptibility tests for determination of ramoplanin MICs
MT Kenny, MA Brackman - Journal of clinical microbiology, 1994 - Am Soc Microbiol
Standard broth microdilution (with and without bovine serum albumin [BSA] supplementation),
tube dilution, and agar dilution susceptibility tests were compared for determining …
tube dilution, and agar dilution susceptibility tests were compared for determining …
Exposure-adjusted safety analyses of the VISION phase 3 trial of 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer.
…, JM Michalski, J Lavalaye, MM Kempel, M Brackman… - 2022 - ascopubs.org
85 Background: In the VISION trial, targeted radioligand therapy with 177 Lu-PSMA-617
significantly prolonged radiographic progression free survival (rPFS) and overall survival when …
significantly prolonged radiographic progression free survival (rPFS) and overall survival when …
Comparative in vitro activity of teicoplanin and vancomycin against United States teicoplanin clinical trial isolates of gram-positive cocci
MT Kenny, JK Dulworth, MA Brackman - Diagnostic microbiology and …, 1991 - Elsevier
In this study, the in vitro activity of teicoplanin and vancomycin was directly compared
against 503 Gram-positive cocci isolated during the US teicoplanin clinical trials. Both anti-biotics …
against 503 Gram-positive cocci isolated during the US teicoplanin clinical trials. Both anti-biotics …