TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses
E Schlosser, M Mueller, S Fischer, S Basta, DH Busch… - Vaccine, 2008 - Elsevier
Dendritic cells phagocytose pathogens leading to maturation and cross-presentation on
MHC class I. We found that the efficiency of cross-priming in mice after vaccination with …
MHC class I. We found that the efficiency of cross-priming in mice after vaccination with …
Balanced scorecard for natural disaster management projects
…, F Gehbauer, S Senitz, M Mueller - Disaster Prevention and …, 2007 - emerald.com
With the recognition of the necessity for effectively and successfully managing natural disaster
projects for saving human lives and preventing and minimizing the impacts of disasters on …
projects for saving human lives and preventing and minimizing the impacts of disasters on …
Automatically testing self-driving cars with search-based procedural content generation
Self-driving cars rely on software which needs to be thoroughly tested. Testing self-driving
car software in real traffic is not only expensive but also dangerous, and has already caused …
car software in real traffic is not only expensive but also dangerous, and has already caused …
Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR−/− mice despite severe hypercholesterolemia
MA Mueller, F Beutner, D Teupser, U Ceglarek… - Atherosclerosis, 2008 - Elsevier
Everolimus inhibits the mammalian target of rapamycin (mTOR) in proliferating cells. It is
widely used in transplant patients and has also been exploited by drug-eluting stents for the …
widely used in transplant patients and has also been exploited by drug-eluting stents for the …
CD8− dendritic cells and macrophages cross-present poly (D, L-lactate-co-glycolate) acid microsphere-encapsulated antigen in vivo
…, S Engelhardt, M Fehlings, M Mueller… - The Journal of …, 2011 - journals.aai.org
The analysis of cell types involved in cross-priming of particulate Ag is essential to understand
and improve immunotherapies using microparticles. In this study, we show that murine …
and improve immunotherapies using microparticles. In this study, we show that murine …
Coencapsulation of tumor lysate and CpG-ODN in PLGA-microspheres enables successful immunotherapy of prostate carcinoma in TRAMP mice
M Mueller, W Reichardt, J Koerner… - Journal of controlled …, 2012 - Elsevier
Biodegradable poly(lactide-co-glycolide) (PLGA) microspheres (MS) deliver antigens and
toll like receptor (TLR) ligands to antigen presenting cells (APC) in vitro and in vivo. PLGA-MS-…
toll like receptor (TLR) ligands to antigen presenting cells (APC) in vitro and in vivo. PLGA-MS-…
Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response
S Fischer, E Schlosser, M Mueller, N Csaba… - Journal of drug …, 2009 - Taylor & Francis
Poly(lactide-co-glycolide) (PLGA) microparticles (MP) possess immunological adjuvant
properties. Yet, exploitation of their full potential has just begun. The purpose of this study was to …
properties. Yet, exploitation of their full potential has just begun. The purpose of this study was to …
[HTML][HTML] Detection of disseminated pancreatic cells by amplification of cytokeratin-19 with quantitative RT-PCR in blood, bone marrow and peritoneal lavage of …
K Hoffmann, C Kerner, W Wilfert, M Mueller… - World journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To evaluate the diagnostic potential of cytokeratin-19 (CK-19) mRNA for the detection
of disseminated tumor cells in blood, bone marrow and peritoneal lavage in patients with …
of disseminated tumor cells in blood, bone marrow and peritoneal lavage in patients with …
The importance of cell–cell interaction dynamics in bottom-up tissue engineering: concepts of colloidal self-assembly in the fabrication of multicellular architectures
Building tissue from cells as the basic building block based on principles of self-assembly is
a challenging and promising approach. Understanding how far principles of self-assembly …
a challenging and promising approach. Understanding how far principles of self-assembly …
[HTML][HTML] Electrospun PCL/PLA scaffolds are more suitable carriers of placental mesenchymal stromal cells than collagen/elastin scaffolds and prevent wound …
E Vonbrunn, M Mueller, M Pichlsberger… - … in Bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) exert beneficial effects during wound healing, and
cell-seeded scaffolds are a promising method of application. Here, we compared the …
cell-seeded scaffolds are a promising method of application. Here, we compared the …