Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept …
…, G Churchyard, LG Bekker, M Nchabeleng… - The Lancet infectious …, 2011 - thelancet.com
Background The MRKAd5 HIV-1 gag/pol/nef subtype B vaccine was designed to elicit T-cell-mediated
immune responses capable of providing complete or partial protection from HIV-1 …
immune responses capable of providing complete or partial protection from HIV-1 …
[HTML][HTML] Vaccine efficacy of ALVAC-HIV and bivalent subtype C gp120–MF59 in adults
…, N Naicker, D Kalonji, M Nchabeleng… - … England Journal of …, 2021 - Mass Medical Soc
Background A safe, effective vaccine is essential to eradicating human immunodeficiency
virus (HIV) infection. A canarypox–protein HIV vaccine regimen (ALVAC-HIV plus AIDSVAX B/…
virus (HIV) infection. A canarypox–protein HIV vaccine regimen (ALVAC-HIV plus AIDSVAX B/…
Clinical and Microbiological Features of Salmonella Meningitis in a South African Population, 2003–2013
…, J Wadula, K Lindeque, M Nchabeleng… - Clinical Infectious …, 2015 - academic.oup.com
Background. The clinical and microbiological characteristics of nontyphoidal Salmonella (NTS)
meningitis in South Africa, where human immunodeficiency virus (HIV) prevalence is …
meningitis in South Africa, where human immunodeficiency virus (HIV) prevalence is …
[HTML][HTML] Effectiveness of the Ad26. COV2. S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B …
…, E van Nieuwenhuizen, K Mngadi, M Nchabeleng… - The Lancet, 2022 - thelancet.com
Background We aimed to assess the effectiveness of a single dose of the Ad26.COV2.S
vaccine (Johnson & Johnson) in health-care workers in South Africa during two waves of the …
vaccine (Johnson & Johnson) in health-care workers in South Africa during two waves of the …
Outbreak of multidrug-resistant tuberculosis in South Africa undetected by WHO-endorsed commercial tests: an observational study
…, M Delmée, L Razwiedani, M Nchabeleng… - The Lancet Infectious …, 2018 - thelancet.com
Background Global roll-out of rapid molecular assays is revolutionising the diagnosis of
rifampicin resistance, predictive of multidrug-resistance, in tuberculosis. However, 30% of the …
rifampicin resistance, predictive of multidrug-resistance, in tuberculosis. However, 30% of the …
Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study
…, LG Bekker, G Churchyard, M Nchabeleng… - The Lancet infectious …, 2014 - thelancet.com
Background The HVTN 503/Phambili study, which assessed the efficacy of the Merck Ad5
gag/pol/nef subtype B HIV-1 preventive vaccine in South Africa, was stopped when futility …
gag/pol/nef subtype B HIV-1 preventive vaccine in South Africa, was stopped when futility …
[HTML][HTML] Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa
…, MO Chukwu, SM Lekala, M Nchabeleng… - BMC research …, 2015 - Springer
Background This study was undertaken to determine the susceptibility profile and the
mechanism of antibiotic resistance in Group B streptococcus (GBS) isolates detected in vaginal …
mechanism of antibiotic resistance in Group B streptococcus (GBS) isolates detected in vaginal …
Rapid development of an integrated network infrastructure to conduct phase 3 COVID-19 vaccine trials
…, S Kotze, O Kasselman, K Gill, M Nchabeleng… - JAMA network …, 2023 - jamanetwork.com
Importance The COVID-19 pandemic has caused millions of infections and deaths and
resulted in unprecedented international public health social and economic crises. As SARS-CoV-…
resulted in unprecedented international public health social and economic crises. As SARS-CoV-…
Analysis of the HIV Vaccine Trials Network 702 phase 2b–3 HIV-1 vaccine trial in South Africa assessing RV144 antibody and T-cell correlates of HIV-1 acquisition risk
…, P Kotze, E Lazarus, M Nchabeleng… - The Journal of …, 2022 - academic.oup.com
Background The ALVAC/gp120 + MF59 vaccines in the HIV Vaccine Trials Network (HVTN)
702 efficacy trial did not prevent human immunodeficiency virus-1 (HIV-1) acquisition. …
702 efficacy trial did not prevent human immunodeficiency virus-1 (HIV-1) acquisition. …
Detection of neonatal unit clusters of Candida parapsilosis fungaemia by microsatellite genotyping: Results from laboratory‐based sentinel surveillance, South Africa …
Neonatal candidaemia is a common, deadly and costly hospital‐associated disease. To
determine the genetic diversity of Candida parapsilosis causing fungaemia in South African …
determine the genetic diversity of Candida parapsilosis causing fungaemia in South African …