The aim of the present study was to investigate the antitumor effect and mechanism of action
of hyperforin in hepatocellular carcinoma (HCC) SK-Hep1 cells in vitro. Cells were treated …

pH responsive chitosan and 3-Glycidyloxypropyl trimethoxysilane (GPTMS) hydrogels were
synthesized by the sol-gel crosslinking reaction. GPTMS was introduced to influence several …

Non-small cell lung cancer (NSCLC) is a malignant lung cancer type with poor prognosis.
NF-κB, the oncogenic transcription factor, has been recognized as an important mediator in …

Regorafenib has been demonstrated in our previous study to trigger apoptosis through
suppression of extracellular signal-regulated kinase (ERK)/nuclear factor-κB (NF-κB) activation in …

Background/Aim: Sorafenib, an oral multi-kinase inhibitor, has been shown to improve the
outcome of patients with osteosarcoma (OS). However, the anti-OS effect and mechanism of …

The fifth subfraction of low-density lipoprotein (L5 LDL) can be separated from human LDL
using fast-protein liquid chromatography with an anion exchange column. L5 LDL induces …

Background: Although both chemotherapy and radiotherapy (RT) can sufficiently maintain
tumor suppression of colorectal cancer (CRC), these treatments may trigger the expression of …

Background/Aim: Non-small cell lung cancer (NSCLC) is the most common type of lung
cancer with poor prognosis. Lenvatinib is a multi-kinase inhibitor that has the potential to …

Zirconium-89 radiolabeled immuno-positron emission tomography ( 89 Zr-iPET) has become
a critical tool for patient stratification before and after immunotherapies for therapeutic …

1737 Objectives PEGylated liposomes are important drug carriers, which can passively
target tumor by enhanced permeability and retention effect in neoplasm lesions. This study …