User profiles for Maneesh Jain
Maneesh JainProfessor, University of Nebraska Medical Center Verified email at unmc.edu Cited by 16258 |
Tumour exosome integrins determine organotropic metastasis
Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
…, PM Grandgenett, MA Hollingsworth, M Jain… - Nature cell …, 2015 - nature.com
Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly
due to delayed detection. We hypothesized that intercellular communication is critical for …
due to delayed detection. We hypothesized that intercellular communication is critical for …
[PDF][PDF] Extracellular vesicle and particle biomarkers define multiple human cancers
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection.
We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in …
We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in …
Targeting the EGFR signaling pathway in cancer therapy
…, MP Ponnusamy, D Haridas, M Jain… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Cancer is a devastating disease; however, several therapeutic advances have
recently been made, wherein EGFR and its family members have emerged as useful …
recently been made, wherein EGFR and its family members have emerged as useful …
Electromagnetically induced transparency: propagation dynamics
A Kasapi, M Jain, GY Yin, SE Harris - Physical review letters, 1995 - APS
We describe the temporal and spatial dynamics of propagating electromagnetically induced
transparency pulses in an optically thick medium. Results include pulse velocities as slow …
transparency pulses in an optically thick medium. Results include pulse velocities as slow …
Multiplexed genotyping with sequence-tagged molecular inversion probes
P Hardenbol, J Banér, M Jain, M Nilsson… - Nature …, 2003 - nature.com
We report on the development of molecular inversion probe (MIP) genotyping, an efficient
technology for large-scale single nucleotide polymorphism (SNP) analysis. This technique …
technology for large-scale single nucleotide polymorphism (SNP) analysis. This technique …
Efficient nonlinear frequency conversion with maximal atomic coherence
M Jain, H Xia, GY Yin, AJ Merriam, SE Harris - Physical review letters, 1996 - APS
We demonstrate efficient nonlinear frequency conversion in atomic Pb vapor under conditions
where the linear susceptibility and the effective nonlinear susceptibility are of the same …
where the linear susceptibility and the effective nonlinear susceptibility are of the same …
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay
…, R Fitzgerald, S Ghose, O Iartchouk, M Jain… - Genome …, 2005 - genome.cshlp.org
Large-scale genetic studies are highly dependent on efficient and scalable multiplex SNP
assays. In this study, we report the development of Molecular Inversion Probe technology with …
assays. In this study, we report the development of Molecular Inversion Probe technology with …
[HTML][HTML] RNA profiles reveal signatures of future health and disease in pregnancy
Maternal morbidity and mortality continue to rise, and pre-eclampsia is a major driver of this
burden 1 . Yet the ability to assess underlying pathophysiology before clinical presentation …
burden 1 . Yet the ability to assess underlying pathophysiology before clinical presentation …
Tumour extracellular vesicles and particles induce liver metabolic dysfunction
…, MA Hollingsworth, PM Grandgenett, M Jain… - Nature, 2023 - nature.com
Cancer alters the function of multiple organs beyond those targeted by metastasis 1 , 2 .
Here we show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …
Here we show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …