Because neurogenesis persists in the adult mammalian brain and can be regulated by
physiological and pathological events, we investigated its possible involvement in the brain's …

Ca 2+ toxicity remains the central focus of ischemic brain injury. The mechanism by which
toxic Ca 2+ loading of cells occurs in the ischemic brain has become less clear as multiple …

Purpose Programmed death-1 (PD-1), a coinhibitory immune signal receptor expressed in T
cells, binds to PD-1 ligand and regulates antitumor immunity. Nivolumab is an anti–PD-1 …

Background—Oxidized LDL (Ox-LDL) seems to play key roles in atherogenesis. Lectinlike
Ox-LDL receptor-1 (LOX-1) is a recently identified cell-surface receptor for Ox-LDL. The …

Primary retroperitoneal neoplasms are a rare but diverse group of benign and malignant
tumors that arise within the retroperitoneal space but outside the major organs in this space. …

A critical event in the early stages of atherosclerosis is the focal accumulation of lipid‐laden
foam cells derived from macrophages. In various cholesterol‐fed animal models of …

Receptor-mediated endocytosis of oxidized low density lipoprotein (OxLDL) by macrophages
has been implicated in foam cell transformation in the process of atherogenesis. Although …

Diagnostic and treatment strategies for gastrointestinal stromal tumors (GISTs) have evolved
greatly since the introduction of molecularly targeted therapies. Although several clinical …

Direct contacts between dendritic cells (DCs) and T cells or natural killer T (NKT) cells play
important roles in primary and secondary immune responses. SR-PSOX/CXC chemokine …

Background— Markers of cardiac injury, including troponin-T (TnT), are used to diagnose
acute coronary syndrome (ACS); however, markers for plaque instability may be more useful …