Glycolysis is increased in cancer cells compared with normal cells. It has been shown that
glucose enters cells via a family of five functional glucose transporters (GLUT). However, …

The mechanism by which afterload reduction increases left ventricular stroke volume while
decreasing left ventricular filling pressure has not previously been established. In 15 patients …

In advanced heart failure, mitral regurgitation increases the burden of the failing ventricle and
decreases effective stroke volume. Although tailored afterload reduction decreases mitral …

Positron emission tomography with 13N-ammonia and 18F-2-deoxygIucose was used to
assess myocardial perfusion and glucose utilization in 51 myocardial segments with a stress …

Positron emission tomography has been shown to distinguish between reversible and
irreversible ischemic tissue injury. Using this technique, 13 patients with acute myocardial …

Previous observations and clinical manifestations suggest the presence of ischemia in the
disproportionately thickened septum of patients with hypertrophic cardiomyopathy. Metabolic …

Pharmacologic stress thallium scintigraphy is commonly performed in the risk assessment of
diabetic patients with nephropathy before kidney and/or pancreas transplantation; however, …

The purpose of this study was to evaluate the prevalence of coronary artery disease and
coronary events during follow-up in patients with asymptomatic carotid stenosis, transient …

To investigate the mechanism by which cardiac glucose utilization increases during hypoxia
and increased work load, we studied the effect of 2 and 14 days of hypobaric hypoxia on the …

Glucose and fructose enter mammalian cells via facilitated diffusion, a process regulated by
five glucose transporter isoforms (GLUT1–5) at the plasma membrane. The tissue-specific …