Purpose. The aim of the present work was to develop a new in vitro system to evaluate oral
absorption of poorly water-soluble drugs by utilizing Caco-2 monolayers. Methods. Caco-2 …

This study was conducted to assess the site of drug absorption in the gastrointestinal (GI)
tract after oral administration. Drug permeability to different regions of rat intestine, jejunum, …

The effects of various experimental conditions on in vitro drug permeability to Caco-2 monolayers
were investigated to determine the optimized conditions for the prediction of intestinal …

The aim of the present work was to establish appropriate conditions for the dissolution/permeation
system (D/P system) to estimate the effect of food intake on oral drug absorption. The …

Development of oral dosage forms containing poorly water-soluble drugs is a major challenge
in the pharmaceutical industry. This paper describes the use of coaxial electrospray …

Micelles formed in the GI tract by bile acid and lecithin play an important role in oral absorption
of poorly soluble drugs. In this situation, the drug molecules are present in equilibrium …

Purpose The aim of the present study is to evaluate the formulation effect on the oral
absorption of poorly water-soluble drugs using a dissolution/permeation system (D/P system). …

The purpose of the present study was to derive a theoretical framework for prediction of the
food effects by interactions with bile micelles on oral drug absorption. The effect of bile …

The usefulness of a dissolution/permeation (D/P) system to predict the in vivo performance
of solid dosage forms containing the poorly soluble drug, fenofibrate, was studied. …

Methane was converted by the photochemical reaction with water vapor at temperatures lower
than 100 C and at atmospheric pressure. The activation of the conversion of methane was …