[HTML][HTML] Antimicrobial peptides: their role as infection-selective tracers for molecular imaging

…, HG Kruger, JR Zeevaart, MM Sathekge - BioMed research …, 2014 - hindawi.com
Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …

[HTML][HTML] Current Status of 68Ga-Pentixafor in Solid Tumours

B Hadebe, MM Sathekge, C Aldous, M Vorster - Diagnostics, 2022 - mdpi.com
Chemokine receptor CXCR4 is overexpressed in neoplasms and its expression is related to
tumour invasion, metastasis and aggressiveness. Ga-Pentixafor is used to non-invasively …

[HTML][HTML] COVID-19 is a multi-organ aggressor: epigenetic and clinical marks

…, S Gordon, P Moura-Alves, MM Sathekge - Frontiers in …, 2021 - frontiersin.org
The progression of coronavirus disease 2019 (COVID-19), resulting from a severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, may be influenced by both genetic …

Evaluating the possible role of 68Ga-citrate PET/CT in the characterization of indeterminate lung lesions

…, H Pottel, C Van de Wiele, MM Sathekge - Annals of Nuclear …, 2014 - Springer
We sought to determine whether PET/CT imaging with 68 Ga-citrate could be of value in
distinguishing benign from malignant lung pathology in a setting with a high prevalence of …

Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area

MM Sathekge, A Maes, H Pottel, A Stoltz… - South African medical …, 2010 - journals.co.za
Objective. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is an accurate
non-invasive imaging test for differentiating benign from malignant solitary pulmonary nodules …

[HTML][HTML] Principal component analysis of texture features derived from FDG PET images of melanoma lesions

DL Anne-Leen, S Machaba, M Alex, DS Bart… - EJNMMI physics, 2022 - Springer
Background The clinical utility of radiomics is hampered by a high correlation between the
large number of features analysed which may result in the “bouncing beta” phenomenon …

[HTML][HTML] Preclinical Research highlighting contemporary targeting mechanisms of radiolabelled compounds for PET based infection imaging

J Kleynhans, MM Sathekge, T Ebenhan - Seminars in Nuclear Medicine, 2023 - Elsevier
It is important to constantly monitor developments in the preclinical imaging arena of infection.
Firstly, novel radiopharmaceuticals with the correct characteristics must be identified to …

Impact of FDG PET on the management of TBC treatment

MM Sathekge, A Maes, M Kgomo, AC Stoltz, H Pottel… - 2010 - repository.up.ac.za
The AIM: of this study is to assess the potential impact of double-phase FDG PET versus
routine staging in HIV-negative patients suffering from tuberculosis. PATIENTS, METHODS: 16 …

[HTML][HTML] Characterization of FDG PET images using texture analysis in tumors of the gastro-intestinal tract: a review

…, MJ Sathekge, A Maes, B De Spiegeleer, M Sathekge… - Biomedicines, 2020 - mdpi.com
Radiomics or textural feature extraction obtained from positron emission tomography (PET)
images through complex mathematical models of the spatial relationship between multiple …

Radiopharmaceutical enhancement by drug delivery systems: A review

…, AF Grobler, T Ebenhan, MM Sathekge… - Journal of controlled …, 2018 - Elsevier
Introduction Drug delivery systems are entities designed to alter the biological behaviour of
the pharmaceutical active ingredients that they carry in order to afford more beneficial …