The evidence base for the use of internal dosimetry in the clinical practice of molecular radiotherapy

L Strigari, M Konijnenberg, C Chiesa, M Bardies… - European journal of …, 2014 - Springer
Molecular radiotherapy (MRT) has demonstrated unique therapeutic advantages in the
treatment of an increasing number of cancers. As with other treatment modalities, there is related …

68Ga-labeled DOTA-peptides and 68Ga-labeled radiopharmaceuticals for positron emission tomography: current status of research, clinical applications, and future …

…, E De Blois, HS Chan, M Konijnenberg… - Seminars in nuclear …, 2011 - Elsevier
In this review we give an overview of current knowledge of 68 Ga-labeled pharmaceuticals,
with focus on imaging receptor-mediated processes. A major advantage of a 68 Ge/ 68 Ga …

[HTML][HTML] Peptide receptor radionuclide therapy using radiolabeled somatostatin analogs: focus on future developments

SM Bison, MW Konijnenberg, M Melis, SE Pool… - Clinical and translational …, 2014 - Springer
Peptide receptor radionuclide therapy (PRRT) has been shown to be an effective treatment
for neuroendocrine tumors (NETs) if curative surgery is not an option. A majority of NETs …

[177Lu-DOTA0,Tyr3]octreotate: comparison with [111In-DTPA0]octreotide in patients

…, WH Bakker, PP Kooij, MW Konijnenberg… - European journal of …, 2001 - Springer
The somatostatin analogue [DOTA 0 ,Tyr 3 ]octreotate has a nine-fold higher affinity for the
somatostatin receptor subtype 2 as compared with [DOTA 0 ,Tyr 3 ]octreotide. Also, labelled …

EANM procedure guidelines for radionuclide therapy with 177Lu-labelled PSMA-ligands (177Lu-PSMA-RLT)

…, M Konijnenberg, K Kopka, M Lassmann… - European journal of …, 2019 - Springer
Prostate-specific membrane antigen (PSMA) is expressed in most prostate cancers and can
be identified by PSMA-ligand imaging, which has already become clinically accepted in …

Radiolabelling DOTA-peptides with 68Ga

…, E de Blois, BF Bernard, M Konijnenberg… - European journal of …, 2005 - Springer
… Louis, MO, USA) and HR Maecke (Basel, Switzerland), and were dissolved in 0.01 M acetic
M. The peptide and the radioactivity were mixed with 1.25 M Na-acetate. pH was measured …

[HTML][HTML] EANM procedure guideline for the treatment of liver cancer and liver metastases with intra-arterial radioactive compounds

M Weber, M Lam, C Chiesa, M Konijnenberg… - European journal of …, 2022 - Springer
Primary liver tumours (ie hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma
(ICC)) are among the most frequent cancers worldwide. However, only 10–20% of …

EANM procedure guideline for the treatment of liver cancer and liver metastases with intra-arterial radioactive compounds

…, B Brans, B Lambert, M Konijnenberg… - European journal of …, 2011 - Springer
… be performed using the equation above, assuming m tumour = 0 (non-compartmental MIRD
… , the two above equations should be applied replacing m liver with m lobe or m segment . …

MIRD pamphlet no. 26: joint EANM/MIRD guidelines for quantitative 177Lu SPECT applied for dosimetry of radiopharmaceutical therapy

M Ljungberg, A Celler, MW Konijnenberg… - Journal of nuclear …, 2016 - Soc Nuclear Med
The accuracy of absorbed dose calculations in personalized internal radionuclide therapy is
directly related to the accuracy of the activity (or activity concentration) estimates obtained at …

[HTML][HTML] EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor-and PSMA-targeting ligands

…, C Stokke, M Konijnenberg, M Cremonesi… - European journal of …, 2022 - Springer
The purpose of the EANM Dosimetry Committee is to provide recommendations and guidance
to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals labelled …