Brain fuel metabolism, aging, and Alzheimer's disease

…, H Begdouri, M Bentourkia, E Turcotte, M Allard… - Nutrition, 2011 - Elsevier
Lower brain glucose metabolism is present before the onset of clinically measurable cognitive
decline in two groups of people at risk of Alzheimer’s disease---carriers of apolipoprotein …

Tracer kinetic modeling in PET

M Bentourkia, H Zaidi - Pet Clinics, 2007 - Elsevier
Molecular imaging using PET provides a unique tool for noninvasively investigating the
biochemistry of living organs. The wide range of radiolabeled molecules makes it possible to …

Comparison of regional cerebral blood flow and glucose metabolism in the normal brain: effect of aging

M Bentourkia, A Bol, A Ivanoiu, D Labar… - Journal of the …, 2000 - Elsevier
The regional cerebral blood flow (rCBF) and metabolic rate for glucose (rCMRGlc) are associated
with functional activity of the neural cells. The present work reports a comparison study …

Initial results from the Sherbrooke avalanche photodiode positron tomograph

…, D Lapointe, D Rouleau, M Bentourkia… - … on Nuclear Science, 1996 - ieeexplore.ieee.org
The design features and engineering constraints of a PET system based on avalanche
photodiode (APD) detectors have been described in a previous report. Here, the authors present …

Investigation of depth-of-interaction by pulse shape discrimination in multicrystal detectors read out by avalanche photodiodes

…, M Bentourkia, R Lecomte, M Andreaco… - … on Nuclear Science, 1999 - ieeexplore.ieee.org
The measurement of depth of interaction (DOI) within detectors is necessary to improve
resolution uniformity across the FOV of small diameter PET scanners. DOI encoding by pulse …

Abnormal in vivo myocardial energy substrate uptake in diet-induced type 2 diabetic cardiomyopathy in rats

…, P Brassard, R Ouellet, M Bentourkia… - American Journal …, 2010 - journals.physiology.org
The purpose of this study was to determine in vivo myocardial energy metabolism and function
in a nutritional model of type 2 diabetes. Wistar rats rendered insulin-resistant and mildly …

Quantitative gated PET for the assessment of left ventricular function in small animals

…, ME Gauthier, A Aliaga, M Bentourkia… - Journal of nuclear …, 2003 - Soc Nuclear Med
18 F-FDG PET can identify areas of myocardial viability and necrosis and provide useful
information on the effectiveness of experimental techniques designed to improve contractile …

Endotoxin-induced heart dysfunction in rats: assessment of myocardial perfusion and permeability and the role of fluid resuscitation

…, M Bentourkia, R Lecomte, M Lessard… - Critical care …, 2006 - journals.lww.com
… The left ventricular diameter during systole, left ventricular diameter during diastole, and
left ventricular ejection fraction (LVEF) were established according to the standards for M-mode …

PET study of 11C-acetoacetate kinetics in rat brain during dietary treatments affecting ketosis

M Bentourkia, S Tremblay, F Pifferi… - American Journal …, 2009 - journals.physiology.org
Normally, the brain's fuel is glucose, but during fasting it increasingly relies on ketones (β-hydroxybutyrate,
acetoacetate, and acetone) produced in liver mitochondria from fatty acid β-…

Study of clinical characteristics in young subjects with developmental coordination disorder

M Farmer, B Echenne, M Bentourkia - Brain and Development, 2016 - Elsevier
Background Developmental Coordination Disorder (DCD) is a chronic neurological disorder
observed in children. DCD is characterized by slowness in activities and motor impairment …