Sex differences in striatal dopamine release in healthy adults
BACKGROUND: Sex differences in addictive disorders have been described. Preclinical
studies have implicated the striatal dopamine system in these differences, but human studies …
studies have implicated the striatal dopamine system in these differences, but human studies …
[HTML][HTML] Relationship between cortisol responses to stress and personality
LM Oswald, P Zandi, G Nestadt, JB Potash… - …, 2006 - nature.com
Although there is growing evidence of links between the cortisol stress response and
personality, the nature of the relationships and the underlying mechanisms require further …
personality, the nature of the relationships and the underlying mechanisms require further …
[HTML][HTML] Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine
There is evidence that stress and glucocorticoids alter drug self-administration and mesolimbic
dopamine (DA) activity in preclinical models. The primary purpose of this study was to …
dopamine (DA) activity in preclinical models. The primary purpose of this study was to …
Gender differences in hypothalamic–pituitary–adrenal (HPA) axis reactivity
M Uhart, RY Chong, L Oswald, PI Lin… - Psychoneuroendocrinology, 2006 - Elsevier
The present study was designed to determine whether there are gender differences in
hormonal response patterns to HPA axis activation. To this end, two methods of activating the …
hormonal response patterns to HPA axis activation. To this end, two methods of activating the …
[HTML][HTML] Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress
Preclinical studies have shown that stress and glucocorticoids increase mesolimbic dopamine
(DA) and thereby facilitate psychostimulant self-administration. The relationship between …
(DA) and thereby facilitate psychostimulant self-administration. The relationship between …
[HTML][HTML] The mu-opioid receptor polymorphism A118G predicts cortisol responses to naloxone and stress
RY Chong, L Oswald, X Yang, M Uhart, PI Lin… - …, 2006 - nature.com
A polymorphism in the mu-opioid receptor (MOR)(A118G) has been shown to increase β-endorphin
binding affinity, theoretically placing greater inhibitory tone on hypothalamic …
binding affinity, theoretically placing greater inhibitory tone on hypothalamic …
History of childhood adversity is positively associated with ventral striatal dopamine responses to amphetamine
Rationale Childhood exposure to severe or chronic trauma is an important risk factor for the
later development of adult mental health problems, such as substance abuse. Even in …
later development of adult mental health problems, such as substance abuse. Even in …
Impulsivity and chronic stress are associated with amphetamine-induced striatal dopamine release
A challenging question that continues to plague the field of addiction is why some individuals
are more vulnerable for substance use disorders than others. Several important risk factors …
are more vulnerable for substance use disorders than others. Several important risk factors …
[HTML][HTML] Early life stress as a predictor of co-occurring alcohol use disorder and post-traumatic stress disorder
During the critical developmental periods of childhood when neural plasticity is high, exposure
to early life stress (ELS) or trauma may lead to enduring changes in physiological stress …
to early life stress (ELS) or trauma may lead to enduring changes in physiological stress …
[HTML][HTML] Hormonal responses to psychological stress and family history of alcoholism
M Uhart, L Oswald, ME McCaul, R Chong… - …, 2006 - nature.com
The present study was designed to determine whether stress hormones and subjective
responses to a psychological stressor were different in nonalcoholic offspring from families with a …
responses to a psychological stressor were different in nonalcoholic offspring from families with a …