Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

Background Amyloid-β (Aβ) plaque formation is a hallmark of Alzheimer's disease (AD) and
precedes the onset of dementia. Aβ imaging should allow earlier diagnosis, but clinical …

18 F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic
feature of Alzheimer disease (AD) and other neurodegenerative disorders. Preclinically, 18 F-…

Purpose: (4S)-4-(3-[ 18 F]fluoropropyl)-l-glutamate (BAY 94-9392, alias [ 18 F]FSPG) is a
new tracer to image x C − transporter activity with positron emission tomography (PET). We …

Purpose: 18 F-labeled small molecules targeting adaptations of tumor metabolism possess
the potential for early tumor detection with high sensitivity and specificity by positron …

The detection of human epidermal growth factor receptor type 2 (HER2) expression in
malignant tumors provides important information influencing patient management. Radionuclide …

Purpose The human monoclonal antibody (MAb) fragment L19-SIP is directed against extra
domain B (ED-B) of fibronectin, a marker of tumour angiogenesis. A clinical …

A new method for the 18 F‐radiolabeling of aromatic compounds based on the aromatic
nucleophilic substitution (S N Ar) reaction using triarylsulfonium salts has been developed. …

Background We assessed the clinical utility of β-amyloid (Aβ) imaging with 18 F-florbetaben
(FBB) in mild cognitive impairment (MCI) by evaluating its prognostic accuracy for …

The extra domain B of fibronectin (ED-B) is a marker of tumor angiogenesis. The human
monoclonal antibody (mAb) L19-SIP (∼80 kDa; SIP is “small immunoprotein”) has been …