Purpose The prognosis of relapsing primary CNS lymphoma (PCNSL) is poor. We report the
results of a prospective multicenter trial of intensive chemotherapy followed by autologous …

Background There is no community standard for the treatment of glioblastoma in patients 70
years of age or older. We conducted a randomized trial that compared radiotherapy and …

Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Object. Although a growing number of authors currently advocate surgery to treat low-grade
gliomas, controversy still persists, especially because of the risk of inducing neurological …

Object Despite better knowledge of cortical language organization, its subcortical
anatomofunctional connectivity remains poorly understood. The authors used intraoperative …

Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …

In contrast to childhood brainstem gliomas, adult brainstem gliomas are rare and poorly
understood. The charts of 48 adults suffering from brainstem glioma were reviewed in order to …

Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-grade
glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

Purpose: Our objective was to identify the genetic changes involved in primary central
nervous system lymphoma (PCNSL) oncogenesis and evaluate their clinical relevance. …

A consecutive series of 143 unselected adult patients with histologically proved World Health
Organization grade II gliomas was reviewed to assess the prognostic value of growth rates …