Beyond the emerging field of oncological ultrasound molecular imaging, the recent significant
advancements in ultrasound and contrast agent technology have paved the way for …

Ultrasound is a widely available, cost-effective, real-time, non-invasive and safe imaging
modality widely used in the clinic for anatomical and functional imaging. With the introduction of …

The combination of target-specific drugs like bevacizumab with chemotherapeutics has
improved treatment efficacy in advanced colorectal cancer (CRC). However, the clinical …

Ultrasound molecular imaging has been developed in the past two decades with the goal of
non-invasively imaging disease phenotypes on a cellular level not depicted on anatomic …

Advances in precision molecular imaging promise to transform our ability to detect, diagnose
and treat disease. Here, we describe the engineering and validation of a new cystine knot …

Abstract Treatment options for patients with hepatocellular carcinoma (HCC) are limited, in
particular in advanced and drug resistant HCC. MicroRNAs (miRNA) are non-coding small …

Purpose: Breast cancer imaging methods lack diagnostic accuracy, in particular for patients
with dense breast tissue, and improved techniques are critically needed. The purpose of this …

Background & Aims RNF43 is an E3 ubiquitin ligase that is recurrently mutated in pancreatic
ductal adenocarcinoma (PDAC) and precursor cystic neoplasms of the pancreas. The …

Power Doppler (PD) imaging is a widely used technique for flow detection. Despite the wide
use of Doppler ultrasound, limitations exist in the ability of Doppler ultrasound to assess …

The ability to cryopreserve natural killer (NK) cells has a significant potential in modern cancer
immunotherapy. Current cryopreservation protocols cause deterioration in NK cell viability …