Rhenium(V) Oxo Complexes of Novel N2S2 Dithiourea (DTU) Chelate Ligands:  Synthesis and Structural Characterization

M Lipowska, BL Hayes, L Hansen, A Taylor… - Inorganic …, 1996 - ACS Publications
The compounds RNHC( S)NH(CH 2 ) n NHC( S)NHR were prepared in a search for new,
relatively small N 2 S 2 ligands. These dithiourea (DTU) ligands are the first chelates …

Linking deprotonation and denticity of chelate ligands. Rhenium (V) oxo analogs of technetium-99m radiopharmaceuticals containing N2S2 chelate ligands

LG Marzilli, MG Banaszczyk, L Hansen… - Inorganic …, 1994 - ACS Publications
Carboxyl groups are important for efficient renal uptake of small anionic molecules.[" mTcO (ECH)]
2_ (ECH= pentaanionic form of (2R, 7/?)-2, 7-dicarboxy-3, 6-diaza-l, 8-octanedithiol (…

Animal evaluation of technetium-99m triamide mercaptide complexes as potential renal imaging agents.

…, AR Fritzberg, S Kasina, L Hansen… - Journal of Nuclear …, 1987 - europepmc.org
Technetium-99m mercaptoacetylglycylglycylglycine (MAG3), a [99mTc] triamide mercaptide
(N3S) compound has been synthesized in an attempt to obviate the stereochemistry …

Rhenium (V) oxo complexes relevant to technetium renal imaging agents derived from mercaptoacetylglycylglycylaminobenzoic acid isomers. Structural and …

L Hansen, R Cini, A Taylor Jr, LG Marzilli - Inorganic Chemistry, 1992 - ACS Publications
Introduction The N3S (triamide monothiol) ligand system forms complexes with both Tcand
Re radionuclides; these complexes have ap-plications in nuclear medicine.[99mTcO (MAG3)] …

The First X-ray Structural Evidence Demonstrating Thiolate Coordination in an Organocobalt B12 Model Complex:  Implications for Methionine Synthase

SM Polson, L Hansen, LG Marzilli - Inorganic Chemistry, 1997 - ACS Publications
Enzyme-bound methyl-B 12 transfers its methyl group to homocysteine during methionine
synthesis. However, treatment of several types of organocobalt B 12 models with arene- and …

[PDF][PDF] Comparison of technetium-99m-LL-EC isomers in rats and humans

A Taylor, L Hansen, D Eshima… - Journal of Nuclear …, 1997 - Soc Nuclear Med
MATERIALS AND METhODS L, L-ethylenedicysteine, D, D-ethylenedicysteine and a mixture
of D, DL, L-and D, L-ethylenedicysteine were prepared according to literature procedures (…

Novel Chemistry of Carbon Bound to Cobalt in Organocobalt Complexes Related to B12

SM Polson, L Hansen, LG Marzilli - Journal of the American …, 1996 - ACS Publications
A rare Co−N−C three-membered ring has been formed by a novel pathway involving a facile
interligand nucleophilic addition of an equatorial nitrogen donor to a ligated axial carbon in …

Synthesis of new N2S2 ligands and Re (V) O (N2S2) analogues of 99mTc renal imaging agents. Characterization by NMR spectroscopy, molecular mechanics …

M Lipowska, L Hansen, R Cini, X Xu, H Choi… - Inorganica chimica …, 2002 - Elsevier
Two new N 2 S 2 ligands [S-trityl-l-cysteine-acetamide-ethanethiol ethyl ester (Tr-l-CAATH 2
-Et, 1) and S-trityl-d-penicillamine-acetamide-(2-methyl-2-propanethiol) ethyl ester (Tr-d-…

Nature of Cysteine-Based Re(V)O(N2S2) Radiopharmaceuticals at Physiological pH Ascertained by Investigation of a New Complex with a Meso N2S2 Ligand …

L Hansen, S Hirota, X Xu, AT Taylor… - Inorganic …, 2000 - ACS Publications
X-ray structural characterization of a new isomer of ReO(TMECH 3 ) revealed that it is anti-ReO(dl-TMECH
3 ) (1). (dl-TMECH 6 is meso-tetramethyl-ethylene-dicysteine prepared from …

The Rare Head-to-Head Conformation of Untethered Lopsided Ligands Discovered in Both Solution and Solid States of 1, 5, 6-Trimethylbenzimidazole Re (V) and Ru …

…, M Iwamoto, E Alessio, L Hansen… - Journal of the …, 1994 - ACS Publications
Metal ligation by N-donor ligands in biological systems involves heterocyclic ligands almost
exclusively. 1 The two most common classes of such ligands are macrocycles (eg, …