The clinical significance of non‐ HLA antibodies on renal allograft survival is a matter of
debate, due to differences in reported results and lack of large‐scale studies incorporating …

The immune system plays a crucial role in many diseases. Activation or suppression of
immunity is often related to clinical outcome. Methods to explore the dynamics of immune …

Whereas regular allocation avoids unacceptable mismatches on the donor organ, allocation
to highly sensitized patients within the Eurotransplant Acceptable Mismatch ( AM ) program …

Background. There is no consensus in the literature on the interpretation of single-antigen
bead positive for a specific HLA antibody. Methods. To inform the debate, we studied the …

The best treatment for patients with end-stage renal disease is kidney transplantation. Although
graft survival rates have improved in the last decades, patients still may lose their grafts …

Background Complement-fixing antibodies against donor HLA are considered a contraindication
for kidney transplant. A modification of the IgG single-antigen bead (SAB) assay allows …

Background Pre-transplant donor-specific anti–human leucocyte antigen (HLA) antibodies (DSAs)
are associated with impaired kidney graft survival while the clinical relevance of non-…

Background Few studies have evaluated the effect of different immunosuppressive strategies
on long-term kidney transplant outcomes. Moreover, as they were usually based on …

In kidney transplantation, survival rates are still partly impaired due to the deleterious effects
of donor specific HLA antibodies (DSA). However, not all luminex‐defined DSA appear to …

In kidney transplantation, donor HLA antibodies are a risk factor for graft loss. Accessibility of
donor eplets for HLA antibodies is predicted by the ElliPro score. The clinical usefulness of …