Brain Tau imaging: food and drug administration approval of 18F-flortaucipir injection

…, AF Fotenos, CJ Ganley, L Marzella - Journal of Nuclear …, 2020 - Soc Nuclear Med
Alzheimer disease (AD) is the most common of neurodegenerative dementias. Currently,
there are more than 5.8 million Americans with AD. Worldwide, there are at least 50 million …

FDA approves Ga 68 PSMA-11 for prostate cancer imaging

…, AA Hofling, A Gorovets, L Marzella - International Journal of …, 2021 - redjournal.org
Prostate cancer is expected to remain the most commonly diagnosed cancer in US men in
2021, with the American Cancer Society estimating 248,530 new cases. 1 Although many …

A trans-agency workshop on the pathophysiology of radiation-induced lung injury

…, MM Satyamitra, N Todd, SJ Wang, L Marzella - 2022 - meridian.allenpress.com
Research and development of medical countermeasures (MCMs) for radiation-induced lung
injury relies on the availability of animal models with well-characterized pathophysiology, …

Prostate cancer theranostics: concurrent approvals by the Food and Drug Administration of the first diagnostic imaging drug indicated to select patients for a paired …

…, J Fallah, S Agrawal, SJ Wang, L Marzella - Journal of Nuclear …, 2022 - Soc Nuclear Med
The expanding field of theranostics combines the use of both diagnostic and therapeutic
drugs that target shared molecular markers of disease. The diagnostic component of a …

A trans-agency workshop on the pathophysiology of radiation-induced lung injury

…, DR Cassatt, L Marzella - Radiation research, 2022 - meridian.allenpress.com
As of January 2021, the US Food and Drug Administration has approved four radiation
exposure medical countermeasures (MCMs) to treat hematological acute effects, but no MCM is …

Quantitative Brain Amyloid PET

…, P Hsieh, PH Kuo, G Farrar, L Marzella - Journal of Nuclear …, 2024 - Soc Nuclear Med
Since the development of amyloid tracers for PET imaging, there has been interest in quantifying
amyloid burden in the brains of patients with Alzheimer disease. Quantitative amyloid …

Gastrointestinal Acute Radiation Syndrome: Mechanisms, Models, Markers, and Medical Countermeasures

TA Winters, L Marzella, O Molinar-Inglis, PW Price… - 2024 - meridian.allenpress.com
There have been a number of reported human exposures to high dose radiation, resulting
from accidents at nuclear power plants (eg, Chernobyl), atomic bombings (Hiroshima and …

Cutaneous radiation injuries: models, assessment and treatments

CI Rios, AL DiCarlo, L Marzella - Radiation research, 2020 - meridian.allenpress.com
Multiple cases of human exposure to radiation have been documented from the atomic
bombings, nuclear power plant disasters and other industrial and medical accidents. Many of …

Development of Drug Products for the Treatment of Acute Radiation Syndrome

M Libero - Disaster Medicine and Public Health Preparedness, 2024 - cambridge.org
The Food and Drug Administration’s (FDA) approval to market drug products for use as
medical countermeasures, to prevent or mitigate injury caused by various threat agents, is …

FDA Approves Lymphoseek to Help Determine Extent of Head and Neck Cancer

O Times - 2014 - journals.lww.com
… “For some patients with head and neck cancer, removal and pathological examination of
lymph nodes draining a primary tumor is an important diagnostic evaluation,” Libero Marzella, …