The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee

…, JR Cook, L Quintanilla-Martinez… - Blood, The Journal …, 2022 - ashpublications.org
Since the publication of the Revised European-American Classification of Lymphoid Neoplasms
in 1994, subsequent updates of the classification of lymphoid neoplasms have been …

Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

…, S Hapfelmeier, L Quintanilla-Martínez… - Infection and …, 2003 - Am Soc Microbiol
Salmonella enterica subspecies 1 serovar Typhimurium is a principal cause of human
enterocolitis. For unknown reasons, in mice serovar Typhimurium does not provoke intestinal …

T-helper-1-cell cytokines drive cancer into senescence

…, HU Häring, R Handgretinger, L Quintanilla-Martinez… - Nature, 2013 - nature.com
Cancer control by adaptive immunity involves a number of defined death 1 , 2 , 3 , 4 , 5 , 6 ,
7 , 8 and clearance 9 , 10 , 11 mechanisms. However, efficient inhibition of exponential …

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

NS Pellegata, L Quintanilla-Martinez… - Proceedings of the …, 2006 - National Acad Sciences
MENX is a recessive multiple endocrine neoplasia-like syndrome in the rat. The tumor
spectrum in MENX overlaps those of human multiple endocrine neoplasia (MEN) types 1 and 2. …

[HTML][HTML] A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

…, T Klopstock, M Ollert, L Quintanilla-Martinez… - Cell, 2009 - cell.com
It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have
been positively selected during human evolution due to effects on aspects of speech and …

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

…, L Quintanilla-Martinez… - Proceedings of the …, 2009 - National Acad Sciences
Ewing tumors (ET) are highly malignant, localized in bone or soft tissue, and are molecularly
defined by ews/ets translocations. DNA microarray analysis revealed a relationship of ET to …

Fulminant EBV+ T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome

L Quintanilla-Martinez, S Kumar, F Fend… - Blood, The Journal …, 2000 - ashpublications.org
This study describes the clinicopathologic features of 5 patients who developed a fulminant
Epstein-Barr virus (EBV)-positive clonal T-cell lymphoproliferative disorder (LPD) after acute …

Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

…, THT Pham, F Fend, ES Jaffe, L Quintanilla-Martinez… - Blood, 2006 - ashpublications.org
To determine whether the PI3K/Akt signaling pathway is involved in the pathogenesis of
mantle cell lymphoma (MCL), we investigated the phosphorylation status of Akt and multiple …

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

…, P Lundberg, L Kanz, L Quintanilla-Martinez… - Nature, 2019 - nature.com
Patients with acute myeloid leukaemia (AML) often achieve remission after therapy, but
subsequently die of relapse 1 that is driven by chemotherapy-resistant leukaemic stem cells (…

Genomic profiling for clinical decision making in lymphoid neoplasms

…, L Pasqualucci, L Quintanilla-Martinez… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …