User profiles for Lena Haeberle
Lena HäberleHeinrich Heine University and University Hospital Verified email at med.uni-duesseldorf.de Cited by 715 |
A Single‐Molecule Bioelectronic Portable Array for Early Diagnosis of Pancreatic Cancer Precursors
A cohort of 47 patients is screened for pancreatic cancer precursors with a portable 96‐well
bioelectronic sensing‐array for single‐molecule assay in cysts fluid and blood plasma, …
bioelectronic sensing‐array for single‐molecule assay in cysts fluid and blood plasma, …
[HTML][HTML] Pathology of pancreatic cancer
L Haeberle, I Esposito - Translational gastroenterology and …, 2019 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy and estimated
to become the second leading cause of cancer-related deaths by 2030. Although overall 5-…
to become the second leading cause of cancer-related deaths by 2030. Although overall 5-…
HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer
…, MA Maestro, N Del Pozo, I Millán, L Haeberle… - The EMBO …, 2020 - embopress.org
Defects in transcriptional regulators of pancreatic exocrine differentiation have been implicated
in pancreatic tumorigenesis, but the molecular mechanisms are poorly understood. The …
in pancreatic tumorigenesis, but the molecular mechanisms are poorly understood. The …
[HTML][HTML] Tumor microenvironment in pancreatic intraepithelial neoplasia
FV Opitz, L Haeberle, A Daum, I Esposito - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive neoplasm
with a poor survival rate. This is mainly due to late detection, which substantially limits …
with a poor survival rate. This is mainly due to late detection, which substantially limits …
Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype
ST Liffers, L Godfrey, L Frohn, L Haeberle, A Yavas… - Gut, 2023 - gut.bmj.com
Objective Due to the limited number of modifiable risk factors, secondary prevention
strategies based on early diagnosis represent the preferred route to improve the prognosis of …
strategies based on early diagnosis represent the preferred route to improve the prognosis of …
Guidelines on the histopathology of chronic pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis …
Background Chronic pancreatitis is a complex multifactorial fibro-inflammatory disease.
Consensus guidelines are needed for the histopathological evaluation of non-autoimmune …
Consensus guidelines are needed for the histopathological evaluation of non-autoimmune …
[HTML][HTML] Bile-based cell-free DNA analysis is a reliable diagnostic tool in pancreatobiliary cancer
C Driescher, K Fuchs, L Haeberle, W Goering, L Frohn… - Cancers, 2020 - mdpi.com
Simple Summary To elucidate and compare the value of plasma and bile as liquid biopsy
source, cfDNA from 80 patients with pancreatobiliary cancers or non-malignant biliary …
source, cfDNA from 80 patients with pancreatobiliary cancers or non-malignant biliary …
Stromal heterogeneity in pancreatic cancer and chronic pancreatitis
L Haeberle, K Steiger, AM Schlitter, SA Safi… - Pancreatology, 2018 - Elsevier
Background/objectives An abundant stromal reaction is a hallmark of pancreatic ductal
adenocarcinoma (PDAC) and chronic pancreatitis (CP). The cells mainly responsible for the …
adenocarcinoma (PDAC) and chronic pancreatitis (CP). The cells mainly responsible for the …
[HTML][HTML] Molecular analysis of cyst fluids improves the diagnostic accuracy of pre-operative assessment of pancreatic cystic lesions
L Haeberle, M Schramm, W Goering, L Frohn… - Scientific reports, 2021 - nature.com
Pancreatic cystic lesions (PCL) are increasingly diagnosed. Endoscopic ultrasound fine-needle
aspiration (EUS-FNA) cytology is often used for diagnostic confirmation but can be …
aspiration (EUS-FNA) cytology is often used for diagnostic confirmation but can be …
Para-aortic lymph nodes and ductal adenocarcinoma of the pancreas: Distant neighbors?
SA Safi, A Rehders, L Haeberle, S Fung, N Lehwald… - Surgery, 2021 - Elsevier
Background Para-aortic lymph nodes in the ductal adenocarcinoma of the pancreatic head
are regarded as distant metastases. Chemotherapy is considered the only treatment option if …
are regarded as distant metastases. Chemotherapy is considered the only treatment option if …