Chelator-Free 64Cu-Integrated Gold Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy
…, Y Wang, J Guo, O Jacobson, D Liu, LP Szajek… - ACS …, 2014 - ACS Publications
Using positron emission tomography (PET) imaging to monitor and quantitatively analyze the
delivery and localization of Au nanomaterials (NMs), a widely used photothermal agent, is …
delivery and localization of Au nanomaterials (NMs), a widely used photothermal agent, is …
89Zr-Oxine Complex PET Cell Imaging in Monitoring Cell-based Therapies
N Sato, H Wu, KO Asiedu, LP Szajek, GL Griffiths… - Radiology, 2015 - pubs.rsna.org
Purpose To develop a clinically translatable method of cell labeling with zirconium 89 ( 89 Zr)
and oxine to track cells with positron emission tomography (PET) in mouse models of cell-…
and oxine to track cells with positron emission tomography (PET) in mouse models of cell-…
Investigation of Zr (IV) and 89 Zr (IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging
Single crystal X-ray diffraction shows that Zr(IV) forms an octa-coordinated complex with 4
bidentate hydroxamates whose solution structures were investigated by utilizing density …
bidentate hydroxamates whose solution structures were investigated by utilizing density …
Single low-dose injection of Evans blue modified PSMA-617 radioligand therapy eliminates prostate-specific membrane antigen positive tumors
…, R Tian, G Niu, Y Ma, L Lang, LP Szajek… - Bioconjugate …, 2018 - ACS Publications
Prostate cancer is the most frequently diagnosed malignant tumor in men worldwide.
Prostate-specific membrane antigen (PSMA) is a surface molecule specifically expressed by …
Prostate-specific membrane antigen (PSMA) is a surface molecule specifically expressed by …
PET imaging of tenascin-C with a radiolabeled single-stranded DNA aptamer
Tenascin-C is an extracellular matrix glycoprotein that is expressed by injured tissues and by
various cancers. Recent publications showed that tenascin-C expression by cancer lesions …
various cancers. Recent publications showed that tenascin-C expression by cancer lesions …
Immuno-PET imaging of the programmed cell death-1 ligand (PD-L1) using a zirconium-89 labeled therapeutic antibody, avelumab
…, KC Lane, S Adler, AT Ton, LP Szajek… - Molecular …, 2019 - journals.sagepub.com
Objective: The goal is to evaluate avelumab, an anti-PD-L1 monoclonal immunoglobulin G
antibody labeled with zirconium-89 in human PD-L1-expressing cancer cells and mouse …
antibody labeled with zirconium-89 in human PD-L1-expressing cancer cells and mouse …
Preparation of cyclotron-produced 186Re and comparison with reactor-produced 186Re and generator-produced 188Re for the labeling of bombesin
…, GJ Ehrhardt, CJ Smith, LP Szajek… - Nuclear medicine and …, 2006 - Elsevier
The radioisotopes 186 Re and 188 Re have been extensively investigated for various forms
of radiotherapy due to their useful and high-abundance β particle emissions, low-…
of radiotherapy due to their useful and high-abundance β particle emissions, low-…
PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A″-DTPA-cetuximab
…, K Garmestani, KE Baidoo, LP Szajek… - European journal of …, 2010 - Springer
Purpose Cetuximab is a recombinant, human/mouse chimeric IgG 1 monoclonal antibody
that binds to the epidermal growth factor receptor (EGFR/HER1). Cetuximab is approved for …
that binds to the epidermal growth factor receptor (EGFR/HER1). Cetuximab is approved for …
[HTML][HTML] PET imaging of CXCR4 using copper-64 labeled peptide antagonist
O Jacobson, ID Weiss, LP Szajek, G Niu, Y Ma… - Theranostics, 2011 - ncbi.nlm.nih.gov
Expression of CXCR4 in cancer has been found to correlate with poor prognosis and
resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide …
resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide …
Bone Marrow Cell Trafficking Analyzed by 89Zr-oxine Positron Emission Tomography in a Murine Transplantation Model
Purpose: The success of hematopoietic stem cell transplantation (HSCT) depends on donor
cell homing to the bone marrow. However, there is no reliable method of noninvasively …
cell homing to the bone marrow. However, there is no reliable method of noninvasively …