Personalised versus standard dosimetry approach of selective internal radiation therapy in patients with locally advanced hepatocellular carcinoma (DOSISPHERE-01 …

…, CR Robert, M Pracht, V Ardisson, L Lenoir… - The lancet …, 2021 - thelancet.com
Background All randomised phase 3 studies of selective internal radiation therapy for advanced
hepatocellular carcinoma published to date have reported negative results. However, …

Dosimetry based on 99mTc-macroaggregated albumin SPECT/CT accurately predicts tumor response and survival in hepatocellular carcinoma patients treated with …

E Garin, L Lenoir, Y Rolland, J Edeline… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Radioembolization of liver cancers using 90 Y-loaded microspheres is experiencing more
widespread use. However, few data are available concerning the doses delivered to the …

High prognostic value of 18F-FDG PET for metastatic gastroenteropancreatic neuroendocrine tumors: a long-term evaluation

H Bahri, L Laurence, J Edeline, H Leghzali… - Journal of Nuclear …, 2014 - Soc Nuclear Med
This study aimed to evaluate the long-term prognostic usefulness of 18 F-FDG PET for
patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEPNETs). Methods: …

Personalized dosimetry with intensification using 90Y-loaded glass microsphere radioembolization induces prolonged overall survival in hepatocellular carcinoma …

…, Y Rolland, J Edeline, N Icard, L Lenoir… - Journal of Nuclear …, 2015 - Soc Nuclear Med
The objective of this study was to evaluate the response rate and survival of hepatocellular
carcinoma portal vein thrombosis (PVT) patients treated with 90 Y-loaded glass microspheres …

Selective internal radiation therapy compared with sorafenib for hepatocellular carcinoma with portal vein thrombosis

…, A Guillygomarc'h, K Boudjema, L Lenoir… - European journal of …, 2016 - Springer
Purpose Tumoural portal vein thrombosis (PVT) is a major prognostic factor in hepatocellular
carcinoma (HCC). The efficacy of sorafenib, the only treatment approved at an advanced …

High impact of macroaggregated albumin‐based tumour dose on response and overall survival in hepatocellular carcinoma patients treated with 90Y‐loaded glass …

…, S Laffont, H Mesbah, LA Haumont, L Lenoir… - Liver …, 2017 - Wiley Online Library
Background & Aims Efficacy of radioembolization is derived from radioinduced damage,
whereas tumour dosimetry is not considered as yet in prospective clinical trials. Objectives This …

Volumetric Changes after 90Y Radioembolization for Hepatocellular Carcinoma in Cirrhosis: An Option to Portal Vein Embolization in a Preoperative Setting?

J Edeline, L Lenoir, K Boudjema, Y Rolland… - Annals of surgical …, 2013 - Springer
Background Contralateral hypertrophy after 90 Y radioembolization has been described in
case reports, but the incidence and quantitative extent of liver volume modifications after this …

[HTML][HTML] Dosimetric parameters predicting contralateral liver hypertrophy after unilobar radioembolization of hepatocellular carcinoma

…, S Le Sourd, M Pracht, S Laffont, L Lenoir… - European journal of …, 2018 - Springer
Purpose This study aimed at identifying prior therapy dosimetric parameters using 99m Tc-labeled
macro-aggregates of albumin (MAA) that are associated with contralateral hepatic …

[HTML][HTML] Usefulness and pitfalls of MAA SPECT/CT in identifying digestive extrahepatic uptake when planning liver radioembolization

L Lenoir, J Edeline, Y Rolland, M Pracht… - European journal of …, 2012 - Springer
Purpose Identifying gastroduodenal uptake of 99m Tc-macroaggregated albumin (MAA),
which is associated with an increased risk of ulcer disease, is a crucial part of the therapeutic …

A MAA-based dosimetric study in patients with intrahepatic cholangiocarcinoma treated with a combination of chemotherapy and 90Y-loaded glass microsphere …

…, A Lievre, H Mesbah, LA Haumont, L Lenoir… - European Journal of …, 2018 - Springer
Purpose Selective internal radiation therapy (SIRT) appears to be an interesting treatment
possibility for locally-advanced intrahepatic cholangiocarcinoma (ICC), yet the appropriate …