Regional changes in the type 1 cannabinoid receptor are associated with cognitive dysfunction in Parkinson's disease

…, R Ahmad, M Crabbé, L Van de Vliet… - European journal of …, 2019 - Springer
Purpose The endocannabinoid system plays a regulatory role in a number of physiological
functions, including motor control but also mood, emotion, and cognition. A number of …

[HTML][HTML] Reduced tendency to attribute mental states to abstract shapes in behavioral variant frontotemporal dementia links with cerebellar structural integrity

…, L Van de Vliet, YA Huang, E Dries, L Van Assche… - NeuroImage: Clinical, 2019 - Elsevier
Abstract Theory of mind (ToM) refers to the ability to attribute mental states to others. Behavioral
variant frontotemporal dementia (bvFTD) is a neurodegenerative disorder characterized …

Behavioral symptoms in premanifest Huntington disease correlate with reduced frontal CB1R levels

J Ceccarini, R Ahmad, L Van de Vliet… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Many Huntington disease (HD) mutation carriers already have cognitive and psychiatric
symptoms in the premanifest (premotor) phase of the disease (pre-HD), but the molecular …

Studying emotion theories through connectivity analysis: evidence from generalized psychophysiological interactions and graph theory

YA Huang, J Jastorff, J Van den Stock, L Van de Vliet… - Neuroimage, 2018 - Elsevier
Psychological construction models of emotion state that emotions are variable concepts
constructed by fundamental psychological processes, whereas according to basic emotion …

Network level characteristics in the emotion recognition network after unilateral temporal lobe surgery

YA Huang, P Dupont, L Van de Vliet… - European Journal of …, 2020 - Wiley Online Library
The human amygdala is considered a key region for successful emotion recognition. We
recently reported that temporal lobe surgery (TLS), including resection of the amygdala, does …

Anterior temporal lobectomy impairs neural classification of body emotions in right superior temporal sulcus and reduces emotional enhancement in distributed brain …

L Van de Vliet, J Jastorff, YA Huang… - Journal of …, 2018 - Soc Neuroscience
Humans with amygdalar lesions show proportional reductions of the emotional response to
facial expressions in the fusiform face area as well as deficits in emotion recognition from …

[HTML][HTML] Face shape and face identity processing in behavioral variant fronto-temporal dementia: a specific deficit for familiarity and name recognition of famous faces

…, J Caekebeke, L Van de Vliet, K Goffin, K Van Laere… - NeuroImage: Clinical, 2016 - Elsevier
Deficits in face processing have been described in the behavioral variant of fronto-temporal
dementia (bvFTD), primarily regarding the recognition of facial expressions. Less is known …

A paleo-neurologic investigation of the social brain hypothesis in frontotemporal dementia

M Vandenbulcke, L Van de Vliet, J Sun… - Cerebral …, 2023 - academic.oup.com
The social brain hypothesis posits that a disproportionate encephalization in primates
enabled to adapt behavior to a social context. Also, it has been proposed that phylogenetically …

[HTML][HTML] Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms

…, CL De Winter, S De Kimpe, JC Van Deutekom… - Molecular Therapy, 2009 - cell.com
Antisense oligonucleotides (AONs) can interfere with mRNA processing through RNase H–mediated
degradation, translational arrest, or modulation of splicing. The antisense approach …

[HTML][HTML] Assessment of the feasibility of exon 45–55 multiexon skipping for Duchenne muscular dystrophy

L Van Vliet, CL de Winter, JCT van Deutekom… - BMC medical …, 2008 - Springer
Background The specific skipping of an exon, induced by antisense oligonucleotides (AON)
during splicing, has shown to be a promising therapeutic approach for Duchenne muscular …