User profiles for Lars Gedda

Lars Gedda

Uppsala university
Verified email at kemi.uu.se
Cited by 2760

Panchromatic ternary polymer dots involving sub-picosecond energy and charge transfer for efficient and stable photocatalytic hydrogen evolution

A Liu, L Gedda, M Axelsson, M Pavliuk… - Journal of the …, 2021 - ACS Publications
Panchromatic ternary polymer dots (Pdots) consisting of two conjugated polymers (PFBT
and PFODTBT) based on fluorene and benzothiadiazole groups, and one small molecular …

111In-benzyl-DTPA–ZHER2: 342, an affibody-based conjugate for in vivo imaging of HER2 expression in malignant tumors

…, K Andersson, D Rosik, L Gedda… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Data on expression of the HER2 (erbB-2) receptor in breast carcinoma make it possible to
select the most efficient treatment. There are strong indications that HER2 expression …

Polymer dots as photoactive membrane vesicles for [FeFe]-hydrogenase self-assembly and solar-driven hydrogen evolution

…, M Lorenzi, DR Morado, L Gedda… - Journal of the …, 2022 - ACS Publications
A semiartificial photosynthesis approach that utilizes enzymes for solar fuel production
relies on efficient photosensitizers that should match the enzyme activity and enable long-term …

[HTML][HTML] Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with 125I-EGF

H Björkelund, L Gedda, P Barta, M Malmqvist… - PLoS …, 2011 - journals.plos.org
The tyrosine kinase inhibitor gefitinib inhibits growth in some tumor types by targeting the
epidermal growth factor receptor (EGFR). Previous studies show that the affinity of the EGF-…

Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents

…, M Johnsson, S Sjöberg, L Gedda - Bioconjugate …, 2002 - ACS Publications
Liposomes are of interest as drug delivery tools for therapy of cancer and infectious diseases.
We investigated conjugation of epidermal growth factor, EGF, to liposomes using the …

Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules

…, I Höidén Guthenberg, L Gedda… - … , Design & Selection, 2011 - academic.oup.com
Emerging evidence suggests that the catalytically inactive ErbB3 (HER3) protein plays a
fundamental role in normal tyrosine kinase receptor signaling as well as in aberrant functioning …

Engineering and characterization of a bispecific HER2× EGFR‐binding affibody molecule

…, J Carlsson, H Brismar, L Gedda… - Biotechnology and …, 2009 - Wiley Online Library
HER2 (human epidermal‐growth‐factor receptor‐2; ErbB2) and EGFR (epidermal‐growth‐factor
receptor) are overexpressed in various forms of cancer, and the co‐expression of both …

[HTML][HTML] Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context

H Björkelund, L Gedda, K Andersson - PloS one, 2011 - journals.plos.org
The interaction of the epidermal growth factor (EGF) with its receptor (EGFR) is known to be
complex, and the common over-expression of EGF receptor family members in a multitude of …

Influence of Chain Length of Gradient and Block Copoly (2‐oxazoline) s on Self‐Assembly and Drug Encapsulation

…, V Bardoula, E Vuorimaa‐Laukkanen, L Gedda… - Small, 2022 - Wiley Online Library
Amphiphilic gradient copolymers represent a promising alternative to extensively used
block copolymers due to their facile one‐step synthesis by statistical copolymerization of …

Flow cytometric in situ proximity ligation analyses of protein interactions and post‐translational modification of the epidermal growth factor receptor family

…, I Weibrecht, U Landegren, L Gedda… - Cytometry Part A …, 2009 - Wiley Online Library
Interactions between members of the epidermal growth factor receptor (EGFR) family mediates
cellular responses to ligand stimulation. Measurement of these interactions could provide …