68Ga-FAPI as a diagnostic tool in sarcoma: data from the 68Ga-FAPI PET prospective observational trial

…, L Umutlu, M Schuler, LE Podleska… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Bone and soft-tissue sarcomas express fibroblast activation protein (FAP) on tumor cells
and associated fibroblasts. Therefore, FAP is a promising therapeutic and diagnostic target. …

Integrated 18F–FDG PET/MRI compared to MRI alone for identification of local recurrences of soft tissue sarcomas: a comparison trial

…, J Kirchner, A Wetter, LE Podleska… - European journal of …, 2017 - Springer
Purpose To assess and compare the diagnostic accuracy of PET/MRI and MRI alone for the
detection of local recurrences of soft tissue sarcomas (STS) after initial surgical resection of …

MedShapeNet--A Large-Scale Dataset of 3D Medical Shapes for Computer Vision

…, F Hoerst, A Brehmer, L Heine, LE Podleska… - arXiv preprint arXiv …, 2023 - arxiv.org
We present MedShapeNet, a large collection of anatomical shapes (eg, bones, organs, vessels)
and 3D surgical instrument models. Prior to the deep learning era, the broad application …

[HTML][HTML] Highly Cancellous Titanium Alloy (TiAl6V4) Surfaces on Three-Dimensionally Printed, Custom-Made Intercalary Tibia Prostheses: Promising Short- to …

WK Guder, J Hardes, M Nottrott, LE Podleska… - Journal of Personalized …, 2021 - mdpi.com
Custom-made, three-dimensionally-printed (3D) bone prostheses gain increasing importance
in the reconstruction of bone defects after musculoskeletal tumor resections. They may …

[HTML][HTML] Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of …

…, C Corless, M Heinrich, J Treckmann, LE Podleska… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gastrointestinal stromal tumors (GIST) exhibit a strong oncogenic dependency on KIT and
KIT inhibitors confer long lasting disease stabilization in the majority of patients. Nonetheless, …

Tumor vascularization and histopathologic regression of soft tissue sarcomas treated with isolated limb perfusion with TNF‐α and melphalan

…, S Bauer, LE Podleska… - Journal of surgical …, 2011 - Wiley Online Library
Background Isolated limb perfusion (TM‐ILP) achieves high response rates in soft tissue
sarcomas (STS). Some tumors show an insufficient association between radiological and …

Secondary angiosarcoma: a fatal complication of chronic lymphedema

…, S Bertram, LE Podleska - Journal of Surgical …, 2020 - Wiley Online Library
Secondary Angiosarcoma (Stewart‐Treves Syndrome) is a rare malignant cutaneous lesion,
which arises in chronic lymphedema of the extremity, often observed after breast cancer …

Dramatic response of a PD-L1-positive advanced angiosarcoma of the scalp to pembrolizumab

…, C Pöttgen, LE Podleska… - JCO Precision …, 2018 - pubmed.ncbi.nlm.nih.gov
… 1 , Lars E Podleska … 1 Rainer Hamacher, Martin Schuler, Sebastian Bauer, Christoph
Pöttgen, Lars E. Podleska, Farhad Farzaliyev, and Hans-Ulrich Steinau, University Hospital …

[HTML][HTML] Lower limb function and quality of life after ILP for soft-tissue sarcoma

LE Podleska, N Kaya, F Farzaliyev, C Pöttgen… - World Journal of …, 2017 - Springer
Background Isolated limb perfusion with TNF-alpha and melphalan (TM-ILP) in combination
with complete tumor resection is an effective treatment option for non-resectable soft-tissue …

[HTML][HTML] Variation in response rates to isolated limb perfusion in different soft-tissue tumour subtypes: an international multi-centre study

…, C Honore, M Rastrelli, N Vassos, LE Podleska… - European Journal of …, 2023 - Elsevier
Objective The aim of this study was to investigate the response rates of different extremity
soft-tissue sarcoma subtypes (eSTS) after isolated limb perfusion (ILP), based on an …