OBJECTIVES: The histologic classification of bladder tumors remains an important predictor
of treatment response and patient outcome, with pure nonurothelial tumors associated with …

Accurate recognition of Gleason pattern (GP) 4 prostate carcinoma (PCa) on needle biopsy
is critical for patient management and prognostication.“Poorly formed glands” are the most …

We assessed the value of fusion 18 F-fluoromethylcholine ( 18 F-choline) PET/MRI for image-guided
(targeted) prostate biopsies to detect significant prostate cancer (Gleason ≥ 3 + 4) …

The differential diagnosis for atypical cribriform lesions of the prostate has become
increasingly complex and includes intraductal carcinoma of the prostate, high-grade prostatic …

Background The study aims to assess the accuracy of multi-parametric prostate MRI (mpMRI)
and 18 F-choline PET/CT in tumor segmentation for clinically significant prostate cancer. F-…

5001 Background: In preclinical CRPC models, PARP1 inhibition synergizes with AR targeted
therapy, especially in ETS fusion-positive tumors. We hypothesized: 1. Co-targeting PARP-…

The objective of this study was to evaluate the cost-effectiveness of 18 F-choline PET/multiparametric
MRI (mpMRI) versus mpMRI alone for the detection of primary prostate cancer with …

Background Recent microarray and sequencing studies of prostate cancer showed multiple
molecular alterations during cancer progression. It is critical to evaluate these molecular …

A prospective single-arm clinical trial was conducted to determine whether 18 F-choline PET/mpMRI
can improve the specificity of multiparametric MRI (mpMRI) of the prostate for …

Sarcosine is a known substrate of proton-coupled amino acid transporters (PATs), which are
overexpressed in selected tissues and solid tumors. Sarcosine, an N-methyl derivative of …