Midbrain functional connectivity and ventral striatal dopamine D2-type receptors: link to impulsivity in methamphetamine users

M Kohno, K Okita, AM Morales, CL Robertson… - Molecular …, 2016 - nature.com
Stimulant use disorders are associated with deficits in striatal dopamine receptor availability,
abnormalities in mesocorticolimbic resting-state functional connectivity (RSFC) and …

[HTML][HTML] Effect of cigarette smoking on a marker for neuroinflammation: a [11C] DAA1106 positron emission tomography study

…, R Enoki, LY Garcia, MS Mamoun, K Okita… - …, 2017 - nature.com
In the brain, microglia continuously scan the surrounding extracellular space in order to
respond to damage or infection by becoming activated and participating in neuroinflammation. …

[HTML][HTML] Quantitative Evaluation of 18F-Flutemetamol PET in Patients With Cognitive Impairment and Suspected Alzheimer's Disease: A Multicenter Study

…, M Mishina, S Mizumura, K Ishii, K Okita… - Frontiers in …, 2021 - frontiersin.org
Background: In clinical practice, equivocal findings are inevitable in visual interpretation of
whether amyloid positron emission tomography (PET) is positive or negative. It is therefore …

Emotion dysregulation and amygdala dopamine D2-type receptor availability in methamphetamine users

K Okita, DG Ghahremani, DE Payer… - Drug and alcohol …, 2016 - Elsevier
Background Individuals who use methamphetamine chronically exhibit emotional and
dopaminergic neurochemical deficits. Although the amygdala has an important role in emotion …

Association between neurite metrics and tau/inflammatory pathology in Alzheimer's disease

…, M Ogawa, N Maikusa, K Okita… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction The molecular mechanism of neurodegeneration, including tau and neurite
complexity, is an important topic in Alzheimer's disease (AD) research. Methods We recruited 27 …

[HTML][HTML] Effectiveness of Information Technology Aided Relapse Prevention Programme in Schizophrenia excluding the effect of user adherence: a randomized …

…, Y Sekine, N Okamura, N Kanahara, K Okita… - Schizophrenia …, 2013 - Elsevier
Background A relapse prevention program called the Information Technology Aided Relapse
Prevention Programme in Schizophrenia (ITAREPS) has been developed and is reported …

[HTML][HTML] Dopamine dysfunction in depression: application of texture analysis to dopamine transporter single-photon emission computed tomography imaging

T Tamura, G Sugihara, K Okita, Y Mukai… - Translational …, 2022 - nature.com
Dopamine dysfunction has been associated with depression. However, results of recent
neuroimaging studies on dopamine transporter (DAT), which reflect the function of the …

[HTML][HTML] The Effects of Citalopram and Thalamic Dopamine D2/3 Receptor Availability on Decision-Making and Loss Aversion in Alcohol Dependence

T Zorick, K Okita, KB Renard, MA Mandelkern… - Psychiatry …, 2022 - hindawi.com
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for patients who
misuse alcohol, especially in the context of comorbid depressive symptoms. Deficits in impulse …

[HTML][HTML] Sex differences in midbrain dopamine D2-type receptor availability and association with nicotine dependence

K Okita, N Petersen, CL Robertson, AC Dean… - …, 2016 - nature.com
Women differ from men in smoking-related behaviors, among them a greater difficulty in
quitting smoking. Unlike female smokers, male smokers have lower striatal dopamine D2-type …

Free water derived by multi‐shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer's disease

…, E Chiba, M Ohnishi, K Kato, K Okita… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction Free‐water (FW) imaging, a new analysis method for diffusion magnetic resonance
imaging (MRI), can indicate neuroinflammation and degeneration. We evaluated FW in …