Previous studies have led to the proposal that patients with Alzheimer's disease (AD) may
have disturbed functional connectivity between different brain regions. Furthermore, recent …

Inflammatory caspases (caspase-1, -4, -5 and -11) are critical for innate defences. Caspase-1
is activated by ligands of various canonical inflammasomes, and caspase-4, -5 and -11 …

Inflammatory caspases cleave the gasdermin D (GSDMD) protein to trigger pyroptosis, a
lytic form of cell death that is crucial for immune defences and diseases. GSDMD contains a …

A superhydrophobic steel surface was prepared through a facile method: combining hydrogen
peroxide and an acid (hydrochloric acid or nitric acid) to obtain hierarchical structures on …

We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within
19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

Objective: We explored whether medical health workers had more psychosocial problems
than nonmedical health workers during the COVID-19 outbreak. Methods: An online survey …

In December 2019, a coronavirus 2019 (COVID-19) disease outbreak occurred in Wuhan,
Hubei Province, China, and rapidly spread to other areas worldwide. Although diffuse alveolar …

Pyroptosis is a form of cell death that is critical for immunity. It can be induced by the
canonical caspase-1 inflammasomes or by activation of caspase-4, -5 and -11 by cytosolic …

"BH3 domain only" members of the BCL-2 family including the pro-apoptotic molecule BID
represent candidates to connect with proximal signal transduction. Tumor necrosis factor α (…