[HTML][HTML] First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)—a systematic review and individual patient data …

…, EJ Pulczynski, A Fosså, Y Okoshi, S Chiba, K Fritsch… - Annals of …, 2015 - Elsevier
Background To investigate prognosis and effects of first-line therapy in elderly primary central
nervous system lymphoma (PCNSL) patients. Patients and methods A systematic review of …

[HTML][HTML] High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study)

K Fritsch, B Kasenda, E Schorb, P Hau, J Bloehdorn… - Leukemia, 2017 - nature.com
To investigate immuno-chemotherapy for elderly immuno-competent patients (⩾ 65 years)
with newly diagnosed primary central nervous system lymphoma, we conducted a multicentre …

High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma: a prospective, single-arm, phase 2 …

…, H Fricker, E Valk, E Schorb, K Fritsch… - The Lancet …, 2016 - thelancet.com
Background High-dose methotrexate-based chemotherapy is standard for primary CNS
lymphoma, but most patients relapse. High-dose chemotherapy with autologous stem cell …

[HTML][HTML] Prognosis of patients with primary central nervous system lymphoma after high-dose chemotherapy followed by autologous stem cell transplantation

…, G Derigs, B Klimm, D Niemann, K Fritsch… - …, 2013 - ncbi.nlm.nih.gov
High-dose chemotherapy followed by autologous stem cell transplantation has been shown
to be feasible and highly effective in newly diagnosed primary central nervous system …

[HTML][HTML] Central nervous system recurrence of systemic lymphoma in the era of stem cell transplantation–an International Primary Central Nervous System Lymphoma …

…, K Jahnke, A Korfel, L Fischer, K Fritsch… - …, 2013 - ncbi.nlm.nih.gov
Autologous stem cell transplantation has greatly improved the prognosis of systemic recurrent
non-Hodgkin’s lymphoma. However, no prospective data are available concerning the …

18F-FDG PET is an independent outcome predictor in primary central nervous system lymphoma

B Kasenda, V Haug, E Schorb, K Fritsch… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Primary central nervous system (CNS) lymphoma is an aggressive non-Hodgkin lymphoma
with poor prognosis. We evaluated pretreatment 18 F-FDG PET as a prognostic marker in …

The MRZ reaction and a quantitative intrathecal IgG synthesis may be helpful to differentiate between primary central nervous system lymphoma and multiple sclerosis

T Hottenrott, E Schorb, K Fritsch, R Dersch, B Berger… - Journal of …, 2018 - Springer
Some patients with primary central nervous system lymphoma (PCNSL) may initially
present with similar clinical, magnetic resonance imaging, and routine cerebrospinal fluid (CSF) …

Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9

K Fritsch, J Finke, C Grüllich - Annals of hematology, 2013 - Springer
Immune surveillance against malignant cells is mediated by cytotoxic T-lymphocytes and NK-cells
(CTL/NK) that induce apoptosis through the granzyme-B-dependent pathway. The …

[HTML][HTML] Sequential high dose immuno-chemotherapy followed by autologous peripheral blood stem cell transplantation for patients with untreated primary central …

G Illerhaus, K Fritsch, G Egerer, M Lamprecht… - Blood, 2012 - Elsevier
Abstract 302 Background: Primary central nervous system lymphoma (PCNSL) is an
aggressive non-Hodgkin′s lymphoma with poor prognosis. Addition of methotrexate (MTX) to …