User profiles for Kristen A. Wangerin

Kristen Wangerin

GE Healthcare
Verified email at ge.com
Cited by 369

Evaluation of lesion detectability in positron emission tomography when using a convergent penalized likelihood image reconstruction method

KA Wangerin, S Ahn, S Wollenweber… - Journal of Medical …, 2017 - spiedigitallibrary.org
We have previously developed a convergent penalized likelihood (PL) image reconstruction
algorithm using the relative difference prior (RDP) and showed that it achieves more …

Quantitative and Qualitative Improvement of Low-Count [68Ga]Citrate and [90Y]Microspheres PET Image Reconstructions Using Block Sequential Regularized …

Y Seo, MM Khalighi, KA Wangerin, TW Deller… - Molecular imaging and …, 2020 - Springer
Purpose There are several important positron emission tomography (PET) imaging scenarios
that require imaging with very low photon statistics, for which both quantitative accuracy …

Clinical Evaluation of 68Ga-PSMA-II and 68Ga-RM2 PET Images Reconstructed With an Improved Scatter Correction Algorithm

KA Wangerin, L Baratto, MM Khalighi… - American Journal of …, 2018 - Am Roentgen Ray Soc
OBJECTIVE. Gallium-68-labeled radiopharmaceuticals pose a challenge for scatter estimation
because their targeted nature can produce high contrast in these regions of the kidneys …

Multicenter clinical trials using 18F-FDG PET to measure early response to oncologic therapy: effects of injection-to-acquisition time variability on required sample size

…, LM Peterson, RK Doot, KA Wangerin… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Uptake time (interval between tracer injection and image acquisition) affects the SUV
measured for tumors in 18 F-FDG PET images. With dissimilar uptake times, changes in tumor …

A virtual clinical trial comparing static versus dynamic PET imaging in measuring response to breast cancer therapy

KA Wangerin, M Muzi, LM Peterson… - Physics in Medicine …, 2017 - iopscience.iop.org
We developed a method to evaluate variations in the PET imaging process in order to characterize
the relative ability of static and dynamic metrics to measure breast cancer response to …

Effect of 18F-FDG uptake time on lesion detectability in PET imaging of early-stage breast cancer

KA Wangerin, M Muzi, LM Peterson, HM Linden… - Tomography, 2015 - mdpi.com
Prior reports have suggested that delayed 18 F-fluorodeoxyglucose positron emission
tomography (FDG-PET) oncology imaging can improve the contrast-to-noise ratio (CNR) for …

Passive electrical model of silicon photomultipliers

KA Wangerin, GC Wang, C Kim… - 2008 IEEE Nuclear …, 2008 - ieeexplore.ieee.org
An electrical model is developed to simulate, characterize, and predict the response of
SSPM detectors for different device geometries and measurement circuit configurations. In …

A path to qualification of PET/MRI scanners for multicenter brain imaging studies: evaluation of MRI-based attenuation correction methods using a patient phantom

…, P Veit-Haibach, KA Wangerin… - Journal of Nuclear …, 2022 - Soc Nuclear Med
PET/MRI scanners cannot be qualified in the manner adopted for hybrid PET/CT devices.
The main hurdle with qualification in PET/MRI is that attenuation correction (AC) cannot be …

Evaluation of attenuation correction in PET/MRI with synthetic lesion insertion

M Hamdi, Y Natsuaki, KA Wangerin… - Journal of Medical …, 2021 - spiedigitallibrary.org
Purpose: One major challenge facing simultaneous positron emission tomography (PET)/
magnetic resonance imaging (MRI) is PET attenuation correction (AC) measurement and …

Attenuation coefficient estimation for PET/MRI with Bayesian deep learning pseudo-CT and maximum-likelihood estimation of activity and attenuation

AP Leynes, S Ahn, KA Wangerin… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
A major remaining challenge for magnetic resonance-based attenuation correction methods
(MRAC) is their susceptibility to sources of magnetic resonance imaging (MRI) artifacts (eg, …