User profiles for Kris Thielemans

Kris Thielemans

- Verified email at vub.ac.be - Cited by 23698

Kris Thielemans

- Verified email at ucl.ac.uk - Cited by 6545

CD8α+ and CD8α Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

…, B Pajak, C Heirman, K Thielemans… - The Journal of …, 1999 - rupress.org
Cells of the dendritic family display some unique properties that confer to them the capacity
to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells (…

[HTML][HTML] Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia

…, J Otten, M Bakkus, K Thielemans… - … England Journal of …, 1998 - Mass Medical Soc
Background and Methods The implications of the detection of residual disease after treatment
of acute lymphoblastic leukemia (ALL) are unclear. We conducted a prospective study at …

[HTML][HTML] Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

…, JC Gutierrez-Ramos, K Thielemans… - The Journal of …, 2000 - Am Soc Clin Investig
The aim of this study was to investigate whether dendritic cells (DCs) can induce sensitization
to aeroallergen in a mouse model of allergic asthma. Ovalbumin-pulsed (OVA-pulsed) or …

STIR: software for tomographic image reconstruction release 2

K Thielemans, C Tsoumpas, S Mustafovic… - Physics in Medicine …, 2012 - iopscience.iop.org
We present a new version of STIR (Software for Tomographic Image Reconstruction), an
open source object-oriented library implemented in C++ for 3D positron emission tomography …

Clearance of influenza virus from the lung depends on migratory langerin+CD11b but not plasmacytoid dendritic cells

…, F Muskens, M Kool, C Baas, K Thielemans… - The Journal of …, 2008 - rupress.org
Although dendritic cells (DCs) play an important role in mediating protection against influenza
virus, the precise role of lung DC subsets, such as CD11b − and CD11b + conventional …

[HTML][HTML] Lung-resident eosinophils represent a distinct regulatory eosinophil subset

…, M Radermecker, K Thielemans… - The Journal of …, 2016 - Am Soc Clin Investig
Increases in eosinophil numbers are associated with infection and allergic diseases, including
asthma, but there is also evidence that eosinophils contribute to homeostatic immune …

Attenuation correction synthesis for hybrid PET-MR scanners: application to brain studies

N Burgos, MJ Cardoso, K Thielemans… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
Attenuation correction is an essential requirement for quantification of positron emission
tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from …

Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation

…, C Heirman, I Van Riet, B Van Camp, K Thielemans - 1992 - ashpublications.org
To investigate whether somatic hypermutation occurs in multiple myeloma (MM) Ig VH region
genes, we have cloned and sequenced the expressed VH genes from five cases of MM. …

Antibodies against immune checkpoint molecules restore functions of tumor-infiltrating T cells in hepatocellular carcinomas

…, J De Jonge, M Gaspersz, H Dong, K Thielemans… - Gastroenterology, 2017 - Elsevier
Background & Aims Ligand binding to inhibitory receptors on immune cells, such as
programmed cell death 1 (PD-1) and cytotoxic T-lymphocyte associated protein 4 (CTLA4), down-…

CD83 expression on dendritic cells and T cells: correlation with effective immune responses

…, JL Aerts, A Bonehill, K Thielemans… - European journal of …, 2007 - Wiley Online Library
Human CD83 is a marker molecule for mature dendritic cells (DC) and is also expressed on
activated B and T cells. Although CD83 has been implicated in immune responses, its …