Background The human tumor microenvironment (TME) is a complex and dynamic milieu of
diverse acellular and cellular components, creating an immunosuppressive environment, …

Background 99m Tc glucarate has recently been reported to be an infarct-avid agent. The
feasibility of imaging with 99m Tc glucarate was evaluated for the early diagnosis of …

A versatile deep-red fluorescent imaging probe is described that is comprised of a bis(zinc(II)-dipicolylamine)
targeting unit covalently attached to a pentamethine carbocyanine …

Definitive diagnosis of acute myocardial infarction early in the process is often difficult. An
imaging agent that localized quickly and specifically in areas of acute necrosis could provide …

Background Similar to other 99m Tc-based infarct-avid agents, 99m Tc-glucarate localizes
in myocardial infarcts. Whether severely ischemic viable myocytes sequester 99m Tc-…

… Koon Yan Pak … Koon Yan Pak … Pak are employees, F. Kiessling is scientific advisor of
Molecular Targeting Technologies, Inc. At all times, the other authors had full control over the study …

Three live rabies virus (RV) recombinant vaccine candidates, SPBNGA, SPBNGA-Cyto c (+),
and SPBNGA-GA, were examined for their production levels and stability. Maximum …

The Lewis a antigen (Lea)- and Lewis b antigen (Leb)-active glycolipids and glycoproteins
in normal colon mucosa, colon carcinoma tumors, and gastrointestinal tumor cell lines were …

99m Tc-Glucarate ( 99m Tc-GLA) is a novel infarct-avid imaging agent. The aim of this study
was to evaluate the role of 99m Tc-GLA for assessing the severity of myocardial ischemia–…

Multimodal tumor imaging with targeted nanoparticles potentially offers both enhanced
specificity and sensitivity, leading to more precise cancer diagnosis and monitoring. We describe …