Extraneuronal cholinergic system in lymphocytes

K Kawashima, T Fujii - Pharmacology & therapeutics, 2000 - Elsevier
Acetylcholine (ACh) is well known as a neurotransmitter in both the central and peripheral
nervous systems in mammalian species. Both muscarinic and nicotinic ACh receptors have …

The lymphocytic cholinergic system and its contribution to the regulation of immune activity

K Kawashima, T Fujii - Life sciences, 2003 - Elsevier
Lymphocytes express most of the cholinergic components found in the nervous system,
including acetylcholine (ACh), choline acetyltransferase (ChAT), high affinity choline transporter, …

Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear …

…, S Yamada, T Ando, F Kazuko, K Kawashima - Neuroscience …, 1999 - Elsevier
Previously, we reported that various levels of acetylcholine (ACh), currently known as a
neurotransmitter, are detectable in the blood of several mammals including humans and that …

[HTML][HTML] Expression and function of the cholinergic system in immune cells

…, H Misawa, S Ono, K Horiguchi, K Kawashima - Frontiers in …, 2017 - frontiersin.org
T and B cells express most cholinergic system components—eg, acetylcholine (ACh), choline
acetyltransferase (ChAT), acetylcholinesterase, and both muscarinic and nicotinic ACh …

[PDF][PDF] Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function

K Kawashima, T Fujii - Front Biosci, 2004 - researchgate.net
Koichiro Kawashima and Takeshi Fujii … It is now clear that ACh, ChAT, and various
mAChRs and nAChRs subtypes are all expressed in nonneuronal mammalian tissues and …

Expression and function of genes encoding cholinergic components in murine immune cells

K Kawashima, K Yoshikawa, YX Fujii, Y Moriwaki… - Life sciences, 2007 - Elsevier
It is now evident that acetylcholine (ACh) synthesized by choline acetyltransferase (ChAT)
and released from T cells during antigen presentation binds to muscarinic and nicotinic ACh …

Evolutional study on acetylcholine expression

…, N Kato, T Fujii, M Seki, T Endo, T Kato, K Kawashima - Life sciences, 2003 - Elsevier
Acetylcholine (ACh) is a well-known neurotransmitter in the cholinergic nervous systems of
vertebrates and insects; however, there is only indirect evidence for its presence in lower …

Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function

K Kawashima, T Fujii, Y Moriwaki, H Misawa - Life sciences, 2012 - Elsevier
Lymphocytes express both muscarinic and nicotinic acetylcholine (ACh) receptors (mAChRs
and nAChRs, respectively), and stimulation of mAChRs and nAChRs produces various …

Multiple reflections of Lamb waves at a delamination

T Hayashi, K Kawashima - Ultrasonics, 2002 - Elsevier
Wave propagation in laminated plates with delaminations was calculated using the semi-analytical
finite element method. The visualization results and deeper numerical analyses …

[HTML][HTML] Physiological functions of the cholinergic system in immune cells

…, H Misawa, S Ono, K Horiguchi, K Kawashima - Journal of …, 2017 - Elsevier
T and B cells, macrophages and dendritic cells (DCs) all express most of the components
necessary for a functional cholinergic system. This includes choline acetyltransferase (ChAT), …