Encouraging results from targeted α-therapy have received significant attention from academia
and industry. However, the limited availability of suitable radionuclides has hampered …

The α v β 3 integrin plays a pivotal role in angiogenesis and tumor metastasis. Angiogenic
blood vessels overexpress α v β 3 integrin, as in tumor neovascularization, and α v β 3 …

Purpose We have developed probes for multiradionuclides radiotheranostics using RGD
peptide ([ 67 Ga]Ga-DOTA-c[RGDf(4-I)K] ([ 67 Ga]1) and Ga-DOTA-[ 211 At]c[RGDf(4-At)K] ([ …

Probes for radiotheranostics could be produced by introducing radionuclides with similar
chemical characteristics into the same precursors. We recently developed an 211 At-labeled …

INTRODUCTION: Based on the concept of bifunctional radiopharmaceuticals, we have
previously developed 186 Re-complex-conjugated bisphosphonate analogs for palliation of …

The biodistribution of 227 Th-EDTMP and retention of its daughter nuclide 223 Ra were
examined. Th-EDTMP was found to show high uptake and long-term retention in bone. The …

It has been reported that sigma receptors are highly expressed in a variety of human tumors.
In this study, we selected (+)‐2‐[4‐(4‐iodophenyl)piperidino] cyclohexanol [(+)‐pIV] as a …

Purpose The aim of this study was to assess whether migration of thallium-201 ( 201 Tl) to
the olfactory bulb were reduced in patients with olfactory impairments in comparison to …

Purpose The aim of this study was to visualize the human olfactory transport pathway to the
brain by performing imaging after nasal thallium-201 ( 201 Tl) administration. Procedures …

Background 211 At is one of the ideal nuclides for targeted radionuclide therapies (TRTs).
Meta-[ 211 At]astatobenzylguanidine ( 211 At-MABG) has been proposed for the treatment of …