The identification of resting state networks (RSNs) and the quantification of their functional
connectivity in resting-state fMRI (rfMRI) are seriously hindered by the presence of artefacts, …

BACKGROUND: Studies examining the way in which cognitive impairment is associated
with depression have produced inconsistent findings. Different severity of depressed mood …

Cumulative meta-analyses are used to evaluate the extent to which further studies are
needed to confirm or refute a hypothesis. We used this approach to assess observational …

Background Inflammatory markers are raised in cross-sectional studies of depressed patients
and may represent an important mediating factor for behaviour, neural plasticity and brain …

Objectives To estimate 10 year decline in cognitive function from longitudinal data in a middle
aged cohort and to examine whether age cohorts can be compared with cross sectional …

In this review of the last 5 years' developments in research into depression we focus on recent
advances and current controversies. We cover epidemiology and basic science as well as …

Background: White matter hyperintensities in MRI scans are age related but appear to be more
prevalent in depressed patients. They may be more pronounced in late onset depression. …

BackgroundThe aetiology of treatment-resistant major depression is little understood; its
apparent intractability may reflect brain abnormality.MethodMagnetic resonance images of the …

Forty patients with a major depressive episode were divided into equal endogenous and
neurotic sub-groups using the Newcastle scale. They were all rated on the 17-item Hamilton …

We reviewed case-control studies of diffusion tensor imaging (DTI) in patients with Alzheimer's
dementia (AD) and mild cognitive impairment (MCI), in order to establish the relative …