Exome sequencing of 343 families, each with a single child on the autism spectrum and at
least one unaffected sibling, reveal de novo small indels and point substitutions, which come …

COVID-19 in patients with cancer is associated with a significantly increased risk of case
fatality, suggesting the need for proactive strategies to reduce likelihood of infection and …

Context Attention-deficit/hyperactivity disorder (ADHD)—characterized by symptoms of
inattention and hyperactivity-impulsivity—is the most prevalent childhood psychiatric disorder that …

As COVID-19 adversely affects patients with cancer, prophylactic strategies are critically
needed. Using a validated antibody assay against SARS-CoV-2 spike protein, we determined a …

Dopamine's role in inhibitory control is well recognized and its disruption may contribute to
behavioral disorders of discontrol such as obesity. However, the mechanism by which …

The value of rewards (natural rewards and drugs) is associated with dopamine increases in
the nucleus accumbens and varies as a function of context. The prefrontal cortex has been …

Context Attention-deficit/hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder
of childhood. There is considerable evidence that brain dopamine is involved in ADHD, …

Obesity has been associated with a higher risk for impaired cognitive function, which most
likely reflects associated medical complications (ie, cerebrovascular pathology). However, …

Loss of control over drug taking is considered a hallmark of addiction and is critical in
relapse. Dysfunction of frontal brain regions involved with inhibitory control may underlie this …

Attention deficit hyperactivity disorder (ADHD) is the most frequent psychiatric disorder in
children, yet data are sparse on its pathophysiology. Particularly relevant are the dopamine …