Insufficient chemotherapy response and rapid disease progression remain concerns for
small-cell lung cancer (SCLC). Oncologists rely on serial CT scanning to guide treatment …

Recent years have played witness to the advent of nuclear theranostics: the synergistic use
of “matched pair” radiopharmaceuticals for diagnostic imaging and targeted radiotherapy. In …

… Author links open overlay panel Sang-gyu Lee a b , Kishore Gangangari a d e , Teja
Muralidhar Kalidindi a , Blesida Punzalan a , Steven M. Larson a b c f , Naga Vara Kishore …

Background The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853,
shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection …

With the successful development and increased use of targeted radionuclide therapy for
treating cancer comes the increased risk of radiation injury to bone marrow—both direct …

… Citation: Fanchon LM, Russell J, Pillarsetty N, O’Donoghue I, Gangangari K, Yu KH, et al.
(2020) … Gangangari KK, Humm JL, Larson SM, Pillarsetty NVK. TMSOTf assisted synthesis of 2'-…

Purpose Sigma-1 receptors (S1Rs) are overexpressed in almost all human cancers, especially
in breast cancers. 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine (IPAG) is a validated high-…

Purpose We studied the effect of varying specific activity of [ 68 Ga]DKFZ-PSMA11 ([ 68 Ga]DP11)
on repeated imaging of prostate-specific membrane antigen-positive (PSMA+) …

[ 18 F]FAC (2’-deoxy-2’-[ 18 F]fluoro-β-D-arabinofuranosylcytosine, 1) is a versatile probe
for imaging deoxycytidine kinase (dCK) expression levels in vivo. dCK is responsible for …

Gemcitabine (gem) is a nucleoside analog that is used to treat pancreatic cancers (PaCa),
which have dismal prognosis and low survival rate. Though gem is used as first line of …