User profiles for Kimberly Kelly

Kimberly Kelly

Professor, Biomedical Engineering UVa
Verified email at virginia.edu
Cited by 8172

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

R Weissleder, K Kelly, EY Sun, T Shtatland… - Nature …, 2005 - nature.com
Nanomaterials with precise biological functions have considerable potential for use in
biomedical applications. Here we investigate whether multivalent attachment of small molecules …

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis

M Nahrendorf, FA Jaffer, KA Kelly, DE Sosnovik… - Circulation, 2006 - Am Heart Assoc
Background— Noninvasive imaging of adhesion molecules such as vascular cell adhesion
molecule-1 (VCAM-1) may identify early stages of inflammation in atherosclerosis. We …

Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle

KA Kelly, JR Allport, A Tsourkas… - Circulation …, 2005 - Am Heart Assoc
Endothelial vascular adhesion molecule-1 (VCAM-1) is a critical component of the leukocyte–endothelial
adhesion cascade, and its strict temporal and spatial regulation make it an …

Plectin-1 as a novel biomarker for pancreatic cancer

…, M Williams, AL Warshaw, SP Thayer, KA Kelly - Clinical Cancer …, 2011 - AACR
Purpose: We are in great need of specific biomarkers to detect pancreatic ductal
adenocarcinoma (PDAC) at an early stage, ideally before invasion. Plectin-1 (Plec1) was recently …

M13-templated magnetic nanoparticles for targeted in vivo imaging of prostate cancer

…, AG Kohli, DS Yun, AM Belcher, KA Kelly - Nature …, 2012 - nature.com
Molecular imaging allows clinicians to visualize the progression of tumours and obtain
relevant information for patient diagnosis and treatment 1 . Owing to their intrinsic optical, …

Targeted delivery of multifunctional magnetic nanoparticles

JR McCarthy, KA Kelly, EY Sun, R Weissleder - 2007 - Future Medicine
Magnetic nanoparticles and their magnetofluorescent analogues have become important tools
for in vivo imaging using magnetic resonance imaging and fluorescent optical methods. A …

[HTML][HTML] Early detection of sporadic pancreatic cancer: summative review

ST Chari, K Kelly, MA Hollingsworth, SP Thayer… - Pancreas, 2015 - journals.lww.com
Pancreatic cancer (PC) is estimated to become the second leading cause of cancer death in
the United States by 2020. Early detection is the key to improving survival in PC. Addressing …

Formation and role of exosomes in cancer

LT Brinton, HS Sloane, M Kester, KA Kelly - Cellular and molecular life …, 2015 - Springer
Exosomes offer new insight into cancer biology with both diagnostic and therapeutic
implications. Because of their cell-to-cell communication, exosomes influence tumor progression, …

Post–COVID-19 conditions among children 90 days after SARS-CoV-2 infection

…, TA Florin, DJ Tancredi, J Xie, K Kim… - JAMA Network …, 2022 - jamanetwork.com
Importance Little is known about the risk factors for, and the risk of, developing post–COVID-19
conditions (PCCs) among children. Objectives To estimate the proportion of SARS-CoV-2…

[HTML][HTML] Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma

KA Kelly, N Bardeesy, R Anbazhagan… - PLoS …, 2008 - journals.plos.org
Background Pancreatic ductal adenocarcinoma (PDAC) carries an extremely poor prognosis,
typically presenting with metastasis at the time of diagnosis and exhibiting profound …