… Clinical and biologic features were compared between groups defined by primary tumor
site using χ 2 tests (for categorical variables) or t test or analysis of variance between …

Background New prognostic markers are needed to identify patients with Ewing sarcoma (EWS)
and osteosarcoma unlikely to benefit from standard therapy. We describe the incidence …

… Vo, MD, 8 Navin Pinto, MD, 9 Yael P. Mosse, MD, 10 John M. Maris, MD, 10 Suzanne
Shusterman, MD, 1 Susan L. … Munshi A, Tanaka T, Hobbs ML, et al.: Vorinostat, a histone …

BACKGROUND MYCN gene amplification (MNA) is a hallmark of aggressive neuroblastoma.
This study was performed to determine univariate and multivariate predictors of tumor MNA…

The metaiodobenzylguanidine (MIBG) scan is one of the most sensitive noninvasive lesion
detection modalities for neuroblastoma. Unlike 123 I-MIBG, 124 I-MIBG allows high-…

Neuroblastoma is one of the most common pediatric cancers. This study used machine
learning (ML) to predict the mortality and a few other investigated intermediate outcomes of …

Most circulating tumor DNA (ctDNA) assays are designed to detect recurrent mutations.
Pediatric sarcomas share few recurrent mutations but rather are characterized by translocations …

Dramatic improvements in clinical outcomes have been seen for children and adolescents
with cancer over the past five decades. 1 The improvement in survival is attributed primarily to …

Background Venetoclax is frequently used as salvage treatment in pediatric, adolescent, and
young adult (AYA) patients with advanced hematologic malignancies. However, more data …

Background Clinical, molecular, and histopathologic features guide treatment for neuroblastoma,
but obtaining tumor tissue may cause complications and is subject to sampling error …