Background Benign prostatic hyperplasia is commonly treated with alpha-adrenergic–receptor
antagonists (alpha-blockers) or 5α-reductase inhibitors. The long-term effect of these …

Context.—The percentage of free prostate-specific antigen (PSA) in serum has been shown
to enhance the specificity of PSA testing for prostate cancer detection, but earlier studies …

Purpose An increasing serum prostate-specific antigen (PSA) level is the initial sign of
recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation …

ContextSalvage radiotherapy may potentially cure patients with disease recurrence after
radical prostatectomy, but previous evidence has suggested that it is ineffective in patients at …

Purpose : The prognostic significance of positive surgical margins (PSM) in radical prostatectomy
(RP) specimens remains unclear. While most studies have concluded that a PSM is an …

Purpose : Prostate specific antigen and free prostate specific antigen have limited specificity
to detect clinically significant, curable prostate cancer, leading to unnecessary biopsy, and …

Objectives. Various methods have been proposed to increase the specificity of prostate-specific
antigen (PSA), including age-specific PSA reference ranges, PSA density (PSAD), and …

Purpose : Men diagnosed with clinically localized prostate cancer have a number of treatment
options available, including watchful waiting, radical prostatectomy and radiation therapy. …

Purpose : We developed a model to predict the side specific probability of extracapsular
extension (ECE) in radical prostatectomy (RP) specimens based on the clinical features of the …

BACKGROUND Survivin counteracts cell death and controls mitotic progression. The
objectives of the current study were to compare the expression patterns of survivin in normal …