Objective Programmed cell death protein 1 (PD-1) checkpoint inhibition and adoptive cellular
therapy have had limited success in patients with microsatellite stable colorectal cancer …

Importance Laparoscopic and robotic techniques have both been well adopted as safe
options in selected patients undergoing hepatectomy. However, it is unknown whether either …

Background Though currently approved immunotherapies, including chimeric antigen
receptor T cells and checkpoint blockade antibodies, have been successfully used to treat …

Background Robotic liver resections (RLR) may have the ability to address some of the
drawbacks of laparoscopic liver resections (LLR) but few studies have done a head‐to‐head …

Background The impact of cirrhosis and portal hypertension on perioperative outcomes of
minimally invasive left lateral sectionectomies remains unclear. We aimed to compare the …

The impact of systemic therapy on the tumor microenvironment has been difficult to study in
human solid tumors. Our protocol describes steps for establishing slice cultures to …

Background Despite the rapid advances that minimally invasive liver resection has gained in
recent decades, open conversion is still inevitable in some circumstances. In this study, we …

Background Robotic hepatectomy (RH) is increasingly utilized for minor and major liver
resections. The IWATE criteria were developed to classify minimally invasive liver resections by …

Although it can promote effector T-cell function, the summative effect of interleukin-10 (IL-10)
in the tumor microenvironment (TME) appears to be suppressive; therefore, blocking this …

Fibrolamellar carcinoma (FLC) is a rare liver tumor driven by the DNAJ-PKAc fusion protein
that affects healthy young patients. Little is known about the immune response to FLC, …