Background We observed a syndrome of intermittent fevers, early-onset lacunar strokes and
other neurovascular manifestations, livedoid rash, hepatosplenomegaly, and systemic …

It is fundamentally important that signaling gradients provide positional information to govern
morphogenesis of multicellular organisms. Morphogen gradients can generate different cell …

The use of CRISPR/Cas9 as a genome-editing tool in various model organisms has radically
changed targeted mutagenesis. Here, we present a high-throughput targeted mutagenesis …

Several major articles from the past decade and beyond conclude the impact of reforestation
or afforestation on water yield is negative: additional forest cover will reduce and removing …

We bring together three decades of research from a boreal catchment to facilitate an improved
mechanistic understanding of surface water dissolved organic carbon (DOC) regulation …

INTRODUCTION Variation in pigmentation among human populations may reflect local
adaptation to regional light environments, because dark skin is more photoprotective, whereas …

As the permafrost region warms, its large organic carbon pool will be increasingly vulnerable
to decomposition, combustion, and hydrologic export. Models predict that some portion of …

Human water use, climate change and land conversion have created a water crisis for
billions of individuals and many ecosystems worldwide. Global water stocks and fluxes are …

This commentary presents a brief outline of a resolution to the elegantly posed double
paradox, which describes a set of issues that hydrologists have grappled with for decades. It is …

Topography is often one of the major controls on the spatial pattern of saturated areas, which
in turn is a key to understanding much of the variability in soils, hydrological processes, …