Nicotinic acetylcholine receptors (nACh receptors2) in jawed vertebrates are prototypical
members of the multisubunit, neurotransmitter-gated superfamily of ion channels (ionotropic …

Tritiated acetylcholine was used to measure binding sites with characteristics of nicotinic
cholinergic receptors in rat brain. Regulation of the binding sites in vivo was examined by …

In Alzheimer's disease (AD), there is a loss of presynaptic cholinergic markers in the
cerebral cortex, but the nature of cholinergic receptor changes is unclear. In this study, [ 3 …

Chronic administration of nicotine increases the density of neuronal cholinergic nicotinic
receptors in cells and in rodent brain, and similar increases have been reported in brains from …

Abstract Comparison of [ 125 I]epibatidine and 5‐[ 125 I]iodo‐3‐(2‐azetidinylmethoxy)pyridine
([ 125 I]A‐85380) autoradiography showed evidence for nicotinic receptor heterogeneity. …

… Kellar KJ In vivo regulation of [jH]acetylcholine recognition sites in brain by nicotinic cholinergic
drugs. J… Data for cerebral cortex are from Schwartz and Kellar (19836). and are …

We stably transfected human kidney embryonic 293 cells with the rat neuronal nicotinic
acetylcholine receptor (nAChR) α3 and β4 subunit genes. This new cell line, KXα3β4R2, …

Cytisine, a ganglionic agonist, competes with high affinity for brain nicotinic cholinergic
receptors labeled by any of several nicotinic 3H-agonist ligands. Here we have examined the …

Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels found
throughout the central and peripheral nervous systems. They are crucial to normal physiology …

We used immunoprecipitation with subunit‐specific antibodies to examine the distribution of
heteromeric neuronal nicotinic acetylcholine receptors (nAChRs) that contain the α5 subunit …