Synthesis and biologic evaluation of novel 18F-labeled probes targeting prostate-specific membrane antigen for PET of prostate cancer
…, H Watanabe, D Matsuoka, K Arimitsu… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a membrane protein highly expressed on
prostate cancer cells and a potential imaging target for diagnosis. F-DCFPyL has been recently …
prostate cancer cells and a potential imaging target for diagnosis. F-DCFPyL has been recently …
Self-assembled ion-pair organocatalysis–asymmetric Baeyer–Villiger oxidation mediated by flavinium–cinchona alkaloid dimer
PP Poudel, K Arimitsu, K Yamamoto - Chemical communications, 2016 - pubs.rsc.org
An ion-pair catalyst generated by assembly of a chiral flavinium and a cinchona alkaloid
dimer for use in asymmetric Baeyer–Villiger oxidation is presented. Ion-pair formation is …
dimer for use in asymmetric Baeyer–Villiger oxidation is presented. Ion-pair formation is …
Synthesis and Biological Evaluation of a Novel Sugar-Conjugated Platinum (II) Complex Having a Tumor-Targeting Effect
M Omokawa, H Kimura, K Arimitsu, Y Yagi, Y Hattori… - ACS …, 2023 - ACS Publications
We designed and synthesized a novel platinum complex conjugated with 2-fluorinated 2-deoxyglucoside,
named FGC-Pt, to capitalize on the Warburg effect and metabolic trapping …
named FGC-Pt, to capitalize on the Warburg effect and metabolic trapping …
Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells
…, K Kanbe, H Matsuda, H Watanabe, K Arimitsu… - Bioorganic & Medicinal …, 2017 - Elsevier
A non-invasive method of pancreatic β-cell mass measurement is needed to enhance our
understanding of the pathogenesis of diabetes, facilitate the early diagnosis of this disease, …
understanding of the pathogenesis of diabetes, facilitate the early diagnosis of this disease, …
First asymmetric total synthesis of (+)-taiwaniaquinol D and (−)-taiwaniaquinone D by using intramolecular Heck reaction
M Ozeki, M Satake, T Toizume, S Fukutome, K Arimitsu… - Tetrahedron, 2013 - Elsevier
The first asymmetric total synthesis of (+)-taiwaniaquinol D and (−)-taiwaniaquinone D
isolated from Taiwania cryptomerioides was attained by using the intramolecular asymmetric …
isolated from Taiwania cryptomerioides was attained by using the intramolecular asymmetric …
[HTML][HTML] Continuous-Flow Synthesis of N-Succinimidyl 4-[18F]fluorobenzoate Using a Single Microfluidic Chip
H Kimura, K Tomatsu, H Saiki, K Arimitsu, M Ono… - PLoS …, 2016 - journals.plos.org
In the field of positron emission tomography (PET) radiochemistry, compact microreactors
provide reliable and reproducible synthesis methods that reduce the use of expensive …
provide reliable and reproducible synthesis methods that reduce the use of expensive …
The synthesis of [18 F] pitavastatin as a tracer for hOATP using the Suzuki coupling
Y Yagi, H Kimura, K Arimitsu, M Ono… - Organic & …, 2015 - pubs.rsc.org
Fluorine-18 labeled radiotracers, such as [18F]fluorodeoxyglucose, can be used as practical
diagnostic agents in positron emission tomography (PET). Furthermore, the properties of …
diagnostic agents in positron emission tomography (PET). Furthermore, the properties of …
Development of 111In-labeled exendin (9-39) derivatives for single-photon emission computed tomography imaging of insulinoma
…, H Fujimoto, K Toyoda, N Fujita, K Arimitsu… - Bioorganic & Medicinal …, 2017 - Elsevier
Insulinoma is a tumor derived from pancreatic β-cells, and the resulting hyperinsulinemia
leads to characteristic hypoglycemia. Recent studies have reported the frequent …
leads to characteristic hypoglycemia. Recent studies have reported the frequent …
Evaluation of 18F-labeled exendin (9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging
…, H Fujimoto, E Mukai, H Kawashima, K Arimitsu… - Bioorganic & Medicinal …, 2018 - Elsevier
β-cell mass (BCM) is known to be decreased in subjects with type-2 diabetes (T2D).
Quantitative analysis for BCM would be useful for understanding how T2D progresses and how …
Quantitative analysis for BCM would be useful for understanding how T2D progresses and how …
Synthesis and evaluation of (−)-and (+)-[11C] galanthamine as PET tracers for cerebral acetylcholinesterase imaging
…, K Miura, Y Nakaya, M Hirasawa, K Arimitsu… - Bioorganic & medicinal …, 2014 - Elsevier
Improved radiopharmaceuticals for imaging cerebral acetylcholinesterase (AChE) are needed
for the diagnosis of Alzheimer’s disease (AD). Thus, 11 C-labeled (−)-galanthamine and …
for the diagnosis of Alzheimer’s disease (AD). Thus, 11 C-labeled (−)-galanthamine and …