Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18
…, D Hollemon, AB Sparks, A Oliphant, K Song - American journal of …, 2012 - Elsevier
OBJECTIVE: We sought to evaluate performance of a noninvasive prenatal test for fetal
trisomy 21 (T21) and trisomy 18 (T18). STUDY DESIGN: A multicenter cohort study was …
trisomy 21 (T21) and trisomy 18 (T18). STUDY DESIGN: A multicenter cohort study was …
Noninvasive prenatal detection and selective analysis of cell-free DNA obtained from maternal blood: evaluation for trisomy 21 and trisomy 18
AB Sparks, CA Struble, ET Wang, K Song… - American journal of …, 2012 - Elsevier
OBJECTIVE: We sought to develop a novel biochemical assay and algorithm for the
prenatal evaluation of risk for fetal trisomy 21 (T21) and trisomy 18 (T18) using cell-free DNA …
prenatal evaluation of risk for fetal trisomy 21 (T21) and trisomy 18 (T18) using cell-free DNA …
Gestational age and maternal weight effects on fetal cell‐free DNA in maternal plasma
E Wang, A Batey, C Struble, T Musci, K Song… - Prenatal …, 2013 - Wiley Online Library
Objective To determine the effects of gestational age and maternal weight on percent fetal
cell‐free DNA (cfDNA) in maternal plasma and the change in fetal cfDNA amounts within the …
cell‐free DNA (cfDNA) in maternal plasma and the change in fetal cfDNA amounts within the …
Selective analysis of cell‐free DNA in maternal blood for evaluation of fetal trisomy
…, M Mitchell, J Stuelpnagel, K Song… - Prenatal …, 2012 - Wiley Online Library
Objective To develop a novel prenatal assay based on selective analysis of cell‐free DNA in
maternal blood for evaluation of fetal Trisomy 21 (T21) and Trisomy 18 (T18). Methods Two …
maternal blood for evaluation of fetal Trisomy 21 (T21) and Trisomy 18 (T18). Methods Two …
Trisomy 13 detection in the first trimester of pregnancy using a chromosome‐selective cell‐free DNA analysis method
…, E Wang, C Struble, A Oliphant, K Song… - … in Obstetrics & …, 2013 - Wiley Online Library
Objective To assess the performance of chromosome‐selective sequencing of maternal
plasma cell‐free DNA ( cfDNA ) in non‐invasive prenatal testing for trisomy 13. Methods Two‐…
plasma cell‐free DNA ( cfDNA ) in non‐invasive prenatal testing for trisomy 13. Methods Two‐…
Clinical utility and cost of non-invasive prenatal testing with cfDNA analysis in high-risk women based on a US population
K Song, TJ Musci, AB Caughey - The journal of maternal-fetal & …, 2013 - Taylor & Francis
Objective: Evaluate the clinical and economic consequences of fetal trisomy 21 (T21) screening
with non-invasive prenatal testing (NIPT) in high-risk pregnant women. Methods: Using …
with non-invasive prenatal testing (NIPT) in high-risk pregnant women. Methods: Using …
Clinical experience of noninvasive prenatal testing with cell‐free DNA for fetal trisomies 21, 18, and 13, in a general screening population
…, S Johnson, TJ Musci, K Song - Prenatal diagnosis, 2013 - Wiley Online Library
Objective Evaluate noninvasive prenatal testing (NIPT) with cell‐free DNA as a screening
method for trisomies 21, 18, and 13 in an obstetrical clinical practice setting. Methods …
method for trisomies 21, 18, and 13 in an obstetrical clinical practice setting. Methods …
Influence of temperature during transportation on cell-free DNA analysis
M Hidestrand, R Stokowski, K Song… - Fetal diagnosis and …, 2012 - karger.com
Objective: To determine the effect of shipping blood in Streck blood collection tubes (BCT)
prior to processing on cell-free DNA (cf-DNA) levels. Methods: Blood was collected in …
prior to processing on cell-free DNA (cf-DNA) levels. Methods: Blood was collected in …
Prenatal screening for fetal aneuploidies with cell-free DNA in the general pregnancy population: a cost-effectiveness analysis
…, J Burigo, T Sharon, K Song - The Journal of Maternal …, 2016 - Taylor & Francis
Objective: To estimate the cost-effectiveness of fetal aneuploidy screening in the general
pregnancy population using non-invasive prenatal testing (NIPT) as compared to first trimester …
pregnancy population using non-invasive prenatal testing (NIPT) as compared to first trimester …
Fetal fraction estimate in twin pregnancies using directed cell-free DNA analysis
CA Struble, A Syngelaki, A Oliphant, K Song… - Fetal diagnosis and …, 2014 - karger.com
Objective: To estimate fetal fraction (FF) in monozygotic and dizygotic twin pregnancies.
Methods: Maternal plasma samples were obtained from 35 monochorionic twin pregnancies …
Methods: Maternal plasma samples were obtained from 35 monochorionic twin pregnancies …