The role of the cell-surface molecule CTLA-4 in the regulation of T cell activation has been
controversial. Here, lymph nodes and spleens of CTLA-4-deficient mice accumulated T cell …

T cell receptor stimulation without costimulation is insufficient for the induction of an optimal
immune response. It is thought that engagement of the CD28 molecule with its ligand B7 …

The Galaxy and Mass Assembly (GAMA) survey has been operating since 2008 February on
the 3.9-m Anglo-Australian Telescope using the AAOmega fibre-fed spectrograph facility to …

Multiple myeloma (MM) is an incurable plasma cell malignancy. The 26S proteasome
inhibitor, bortezomib, selectively induces apoptosis in MM cells; however, the nature of its …

The expression of the V(D)J [variable (diversity) joining elements] recombination activating
genes, RAG-1 and RAG-2, has been examined during T cell development in the thymus. In …

We conducted a controlled, blinded, multicenter study of disulfiram treatment of alcoholism
in 605 men randomly assigned to 250 mg of disulfiram (202 men); 1 mg of disulfiram (204 …

Chinese hamster ovary (CHO)–derived cell lines are the preferred host cells for the
production of therapeutic proteins. Here we present a draft genomic sequence of the CHO-K1 …

This paper describes the first catalogue of photometrically derived stellar mass estimates for
intermediate-redshift (z < 0.65; median z= 0.2) galaxies in the Galaxy And Mass Assembly (…

Background There is no practical and reliable premortem test for Creutzfeldt–Jakob disease
and the related transmissible spongiform encephalopathies. Two proteins, designated 130 …

The Galaxy And Mass Assembly (GAMA) survey is one of the largest contemporary
spectroscopic surveys of low redshift galaxies. Covering an area of ∼286 deg 2 (split among five …