Putative transport mechanism and intracellular fate of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid in human prostate cancer

…, M Yoshimoto, M Kobayashi, K Ohe… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Trans-1-amino-3- 18 F-fluorocyclobutanecarboxylic acid (anti– 18 F-FACBC) is an amino acid
PET tracer that has shown promise for visualizing prostate cancer. Therefore, we aimed to …

Predominant contribution of L-type amino acid transporter to 4-borono-2-18F-fluoro-phenylalanine uptake in human glioblastoma cells

…, H Kurihara, N Honda, K Kawai, K Ohe… - Nuclear medicine and …, 2013 - Elsevier
INTRODUCTION: 4-Borono-2- 18 F-fluoro-phenylalanine ( 18 F-FBPA) has been used to
anticipate the therapeutic effects of boron neutron capture therapy (BNCT) with 4-borono-L-…

Transport mechanism of 11C-labeled L-and D-methionine in human-derived tumor cells

M Kobayashi, F Hashimoto, K Ohe, T Nadamura… - Nuclear medicine and …, 2012 - Elsevier
INTRODUCTION: S-methyl- 11 C-labeled l- and d-methionine ( 11 Cl- and d-MET) are
useful as radiotracers for tumor imaging. However, it is not known whether the transport …

Arterial 18F-fluorodeoxyglucose uptake reflects balloon catheter-induced thrombus formation and tissue factor expression via nuclear factor-κB in rabbit …

…, C Sugita, T Iwakiri, N Okuyama, K Ohe… - Circulation …, 2013 - jstage.jst.go.jp
Background: Imaging modalities to assess atherosclerotic plaque thrombogenicity have not
been established, so in this study the relationship between [18 F]-fluorodeoxyglucose (18 F-…

Regulation of alternative splicing of the receptor for advanced glycation endproducts (RAGE) through G-rich cis-elements and heterogenous nuclear …

K Ohe, T Watanabe, S Harada… - The journal of …, 2010 - academic.oup.com
Receptor for advanced glycation endproducts (RAGE) is a cell-surface receptor. The binding
of ligands to membrane-bound RAGE (mRAGE) evokes cellular responses involved in …

Functional characterization of apical transporters expressed in rat proximal tubular cells (PTCs) in primary culture

…, M Yoshifuji, T Gose, Y Shirasaka, K Ohe… - Molecular …, 2011 - ACS Publications
Since in vitro cell culture models often show altered apical transporter expression, they are
not necessarily suitable for the analysis of renal transport processes. Therefore, we aimed …

Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains

…, K Tsuneyama, Y Yamamoto, K Ohe… - Archives of histology …, 2007 - jstage.jst.go.jp
The receptor for advanced glycation endproducts (RAGE) is a cell-surface multiligand receptor,
which interacts with amyloid β (Aβ), a key protein in Alzheimer's disease (AD). RAGE-Aβ …

Usefulness of system A amino acid transport PET imaging with C-11-MeAIB in diagnosing brain tumors: A comparison study with C-11-Methionine PET imaging

…, Y Kishibe, M Takahashi, M Kobayashi, K Ohe… - 2012 - Soc Nuclear Med
1992 Objectives We have presented system A amino acid PET imaging with [N-methyl-C-11]α-methylaminoisobutyric
acid (MeAIB) in patients with glioblastoma multiforme (GBM) as a …

[PDF][PDF] Radioiodinated 6-iodo-D-meta-tyrosine: Characterization of Uptake in DLD-1 Colon Cancer Cells and Biodistribution in Mice

N Shikano, N Yagi, R Nishii, K Ohe… - 茨城県立医療 …, 2019 - kawai.w3.kanazawa-u.ac.jp
Introduction: 123I-6-iodo-D-meta-tyrosine (123I-6-D-mTyr) is an iodine-labeled D-amino acid
employed potentially in molecular imaging of tumors. We used its 125I-labeled analogue (6…

[PDF][PDF] Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains

…, H Akatsu, K Tsuneyama, Y Yamamoto, K Ohe… - 2007 - kanazawa-u.repo.nii.ac.jp
The receptor for advanced glycation endproducts (RAGE) is a cell-surface multiligand receptor,
which interacts with amyloid fi (Af), a key protein in Alzheimer's disease (AD). RAGE-Af …