'Ischemic tolerance'phenomenon found in the brain
K Kitagawa, M Matsumoto, M Tagaya, R Hata, H Ueda… - Brain research, 1990 - Elsevier
We investigated the possibility that neuronal cells given a mild ischemic treatment sufficient
to perturb the cellular metabolism acquired tolerance to a subsequent, and what would be …
to perturb the cellular metabolism acquired tolerance to a subsequent, and what would be …
Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis
…, S Holewijn, A Ikeda, M Kavousi, K Kitagawa… - Jama, 2012 - jamanetwork.com
Context The evidence that measurement of the common carotid intima-media thickness (CIMT)
improves the risk scores in prediction of the absolute risk of cardiovascular events is …
improves the risk scores in prediction of the absolute risk of cardiovascular events is …
The effect of crosslinking on the mechanical properties of polylactic acid/polycaprolactone blends
T Semba, K Kitagawa, US Ishiaku… - Journal of applied …, 2006 - Wiley Online Library
The improvement of the brittle behavior of Polylactic acid (PLA) resin was studied by blending
it with Polycaprolactone (PCL) resin. These materials were fabricated into the compressed …
it with Polycaprolactone (PCL) resin. These materials were fabricated into the compressed …
'Ischemic tolerance'phenomenon detected in various brain regions
K Kitagawa, M Matsumoto, K Kuwabara, M Tagaya… - Brain research, 1991 - Elsevier
We investigated the effects of mild and non-lethal ischemic insult on neuronal death
following subsequent lethal ischemic stress in various brain regions, using a gerbil model of …
following subsequent lethal ischemic stress in various brain regions, using a gerbil model of …
Neurogenesis by progenitor cells in the ischemic adult rat hippocampus
Y Yagita, K Kitagawa, T Ohtsuki, K Takasawa, T Miyata… - Stroke, 2001 - Am Heart Assoc
Background and Purpose— Recently, there has been great interest in adult neurogenesis.
We investigated whether transient forebrain ischemia could influence the proliferation of …
We investigated whether transient forebrain ischemia could influence the proliferation of …
C-reactive protein is an independent predictor of the rate of increase in early carotid atherosclerosis
H Hashimoto, K Kitagawa, H Hougaku, Y Shimizu… - Circulation, 2001 - Am Heart Assoc
Background—An elevated plasma concentration of high-sensitivity C-reactive protein (hs-CRP)
is a strong predictor of cardiovascular events. However, there have been no longitudinal …
is a strong predictor of cardiovascular events. However, there have been no longitudinal …
Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats
T Mabuchi, K Kitagawa, T Ohtsuki, K Kuwabara… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—The purpose of this study was (1) to examine the contribution of
microglia and macrophages with their interleukin-1β production and (2) to assess the …
microglia and macrophages with their interleukin-1β production and (2) to assess the …
Efficacy and safety of adjusted-dose prasugrel compared with clopidogrel in Japanese patients with acute coronary syndrome–the PRASFIT-ACS study–
…, H Yokoi, S Nanto, M Takayama, K Kitagawa… - Circulation …, 2014 - jstage.jst.go.jp
Background: Prasugrel is an antiplatelet agent that shows more prompt, potent, and consistent
platelet inhibition than clopidogrel. The objective of this study was to confirm the efficacy …
platelet inhibition than clopidogrel. The objective of this study was to confirm the efficacy …
Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo
T Mabuchi, K Kitagawa, K Kuwabara… - Journal of …, 2001 - Soc Neuroscience
Although accumulating evidence indicates that cAMP response element-binding protein (CREB)
phosphorylation mediates not only synaptic plasticity but also survival of certain neurons…
phosphorylation mediates not only synaptic plasticity but also survival of certain neurons…
Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice: evaluation of the patency of the posterior communicating artery
K Kitagawa, M Matsumoto, G Yang… - Journal of Cerebral …, 1998 - journals.sagepub.com
Cerebral ischemia models using mice have drawn increasing attention, particularly because
of the availability of transgenic animals. However, the variability of intracranial vasculature …
of the availability of transgenic animals. However, the variability of intracranial vasculature …