Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart

T Higuchi, M Anton, K Dumler, S Seidl… - Journal of Nuclear …, 2009 - Soc Nuclear Med
There is a need for in vivo monitoring of cell engraftment and survival after cardiac cell
transplantation therapy. This study assessed the feasibility and usefulness of combined PET and …

Tetracycline‐regulated bone morphogenetic protein 2 gene expression in lentivirally transduced primary rabbit chondrocytes for treatment of cartilage defects

D Wübbenhorst, K Dumler, B Wagner… - Arthritis & …, 2010 - Wiley Online Library
Objective Treatment of cartilage defects is still challenging, primarily because of the poor self‐healing
capacity of articular cartilage. Gene therapy approaches have gained …

Reporter gene PET for monitoring survival of transplanted endothelial progenitor cells in the rat heart after pretreatment with VEGF and atorvastatin

T Higuchi, M Anton, A Saraste, K Dumler… - Journal of Nuclear …, 2009 - Soc Nuclear Med
It has been suggested that vascular endothelial growth factor (VEGF) and statins enhance the
survival, proliferation, and function of endothelial progenitor cells (EPCs). We investigated …

[PDF][PDF] Outstanding JNM Articles for 2009

R Swanson, G Chakraborty, CH Wang, R Rockne… - J Nucl …, 2009 - Soc Nuclear Med
Heinrich R. Schelbert, MD, PhD, editor-in-chief of The Journal of Nuclear Medicine (JNM),
and his associate editors and editorial board announced in June the articles chosen as the …

[HTML][HTML] Reliability of human retina organoid generation from hiPSC-derived neuroepithelial cysts

…, F Wagner, T Kurth, N Dumler… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
The possible applications for human retinal organoids (HROs) derived from human induced
pluripotent stem cells (hiPSC) rely on the robustness and transferability of the methodology …

Optimizing adenoviral transduction of endothelial cells under flow conditions

M Anton, A Wolf, O Mykhaylyk, C Koch… - Pharmaceutical …, 2012 - Springer
Purpose To target adenoviral vectors to cells of the vasculature and shielding vectors from
inactivation by the immune system. Methods Complexes of reporter gene expressing …

An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic …

Y Kostova, K Mantwill, PS Holm, M Anton - Cancer Gene Therapy, 2015 - nature.com
We investigated the novel recombinant oncolytic adenovirus Ad-delo-sr39TK-RGD, armed
with a mutant herpes simplex virus type 1 thymidine kinase (HSV1-sr39TK) as a suicide gene, …

[HTML][HTML] Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells

MD Kolba, W Dudka, M Zaręba-Kozioł, A Kominek… - Cell death & …, 2019 - nature.com
Intercellular communication within the bone marrow niche significantly promotes leukemogenesis
and provides protection of leukemic cells from therapy. Secreted factors, intercellular …

[PDF][PDF] A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity

P Meiser, MA Knolle, A Hirschberger, GP de Almeida… - Cancer Cell, 2023 - cell.com
Type 1 conventional dendritic cells (cDC1) can support T cell responses within tumors but
whether this determines protective versus ineffective anti-cancer immunity is poorly understood…

XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells

A Wahida, M Müller, A Hiergeist, B Popper… - Science …, 2021 - science.org
Deficiency in X-linked inhibitor of apoptosis protein (XIAP) is the cause for X-linked
lymphoproliferative syndrome 2 (XLP2). About one-third of these patients suffer from severe and …