In most mammals the pancreas develops from the foregut endoderm as ventral and dorsal
buds. These buds fuse and develop into a complex organ composed of endocrine, exocrine …

Sonic hedgehog (Shh) specifies the identity of both motor neurons (MNs) and interneurons
with morphogen-like activity. Here, we present evidence that the homeodomain factor HB9 is …

Methods: We used US national HIV surveillance data (cases≥ 13 years old) to model life
expectancy after an HIV diagnosis using the life table approach. We then compared life …

Synthetic high affinity peroxisome proliferator-activated receptor (PPAR) agonists are known,
but biologic ligands are of low affinity. Oxidized low density lipoprotein (oxLDL) is …

The metabolites of arachidonic acid form a very large class of biologically active lipid
substances generated within cells by several different oxygenase reactions. The prostaglandins (…

Intermuscular adipose tissue (IMAT) is negatively related to insulin sensitivity, but a causal
role of IMAT in the development of insulin resistance is unknown. IMAT was sampled in …

BACKGROUND. Accumulation of diacylglycerol (DAG) and sphingolipids is thought to promote
skeletal muscle insulin resistance by altering cellular signaling specific to their location. …

Objective. The purpose of this study was to assess an alternative statistical approach—multiple
imputation—to risk factor redistribution in the national human immunodeficiency virus (…

Qualitative methodology based on action research identified challenges when caring for
persons with advanced dementia, as perceived by key professional providers. Data collection …

Conserved structural motifs on pathogens trigger pattern recognition receptors present on
APCs such as dendritic cells (DCs). An important class of such receptors is the Toll-like …